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Protein Overview: SPAC9E9.09c

General Information:
Name(s) found: SPAC9E9.09c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • aldehyde dehydrogenase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 503 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mitochondrial matrix [ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: ethanol catabolic process [ISSLink to PubMed article]
    NADPH regeneration [ISS]
    cellular response to stress [IEPLink to PubMed article]
    pyruvate metabolic process [ISS]
    acetate biosynthetic process [ISS]
    Molecular Function: aldehyde dehydrogenase (NAD) activity [ISS]
    aldehyde dehydrogenase [NAD(P)+] activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTKLVDHVE ITVPTGKTYI QPVGLFINNQ HVDSVHGGRV KVYSPSTEKL ICEVADADEE  60
   61 DVDIAVKVAR AAFQTDAPWR KFSSAQRGRC LSRLADCIEQ NLEYLASIET LDNGKSITLA 120
  121 RGDVQAAADC FRYYGGWADK DYGQTIETDI KRFAYTRHEP IGVCGQIIPW NFPFLMCAWK 180
  181 IAPAVACGNT IILKTAELTP LSALCLTKFV PECGFPPGVI NVLSGDGRRC GNAISSHMDI 240
  241 DKVAFTGSTG VGRMVMRAAA SSNLKKVTLE LGGKSPNIVF NDADLDSAAV WTNYGIFYNS 300
  301 GQVCCAGSRV YVQEDVYDEF IKRMVAKAKT LKVGDPFAED TFQGAQVSKQ QYERIVSYIE 360
  361 SGIAHGAKLE IGGKRHGNLG YFVEPTILSN VTEDMAVGKE EIFGPVLAVI KFKTIEEAIR 420
  421 RGNNSTYGLA AGVHTNNITN AIKVSNALEA GTVWVNCYNL LHHQIPFGGY KESGIGRELG 480
  481 SYGLTNYTQT KAVHINLGMD SPI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..503] PSI-BLAST 178.0 Aldehyde reductase (dehydrogenase), ALDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.09598561374689 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  4.2273960318884 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  3.49281413016612 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.99564252244797 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • aminobutyraldehyde dehydrogenase activity
    		•  2.35958138496479 bayes_pls_golite062009
  • acyl-CoA binding
    		•  2.26220696569489 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  0.882678635212924 bayes_pls_golite062009
  • retinoid binding
    		•  0.801468424891608 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.719034630339067 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle