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Protein Overview: clr2

General Information:
Name(s) found: clr2 / SPAC1B3.17 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • chromatin silencing protein Clr2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 537 amino acids

    Gene Ontology:
    Cellular Component: mating-type region heterochromatin [IDALink to PubMed article]
    telomeric heterochromatin [IDALink to PubMed article]
    NuRD complex [IDALink to PubMed article]
    rDNA heterochromatin [IDALink to PubMed article]
    centromeric heterochromatin [IDALink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    chromatin silencing at centromere [IMPLink to PubMed articleLink to PubMed article]
    chromatin silencing at rDNA [IMPLink to PubMed articleLink to PubMed article]
    chromatin silencing [IMPLink to PubMed article]
    chromatin silencing at silent mating-type cassette [IMPLink to PubMed articleLink to PubMed article]
    histone deacetylation [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAITCVWSD GRSDTWPNVN GHSRTRSVPS LKPLPHQDSK NLLYRQICGR LLAQHVFGGA  60
   61 GSTQPILNQL CKRLSTGNPN NTNASTVVTA PEKNVVSARH VRPNPKSSKD TLEKQPKYSS 120
  121 QIYLTDSFEN YYLASLPTNY QLYQRDSNRE NGNGKREFWL YGHPSGRPFR SVNDFLHHLY 180
  181 WLISDLTRNE STCCCVLCSG NMTRVRKNLQ KENERMFHEC KDDTYTWPSS YRLGEVVWID 240
  241 INNELIPAII VARNLINYES NQMDAVKLIS DTFVEPYQYH CKQLGNSRYY FDMAAADIEP 300
  301 WSRHPLDLQK QEHLVAHSIC QTWNLFGIFQ PLEGIDMEEP KFHDENYSIP LTVLPTFGGE 360
  361 SNSLDDHFYG IFRGAEKLWI NDLCVISTSS LPSVLQKTSF MYISDIYVNE DDIVCFQGSL 420
  421 WTQIDKNALD YNDSADNIDE HKDDLKELPR RLQMVSKLSN TYFRCLHDKS VEYVCPFADV 480
  481 LGRWYEPWFV KGDLNYTSEV KERTSSRLSA VGSENWVDDD FYEYLLSEID MVSAVVM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] deduced N/A No confident structure predictions are available.
    2 View Details [117..187] MSA 1.002976 View MSA. No confident structure predictions are available.
    3 View Details [188..337] deduced N/A No confident structure predictions are available.
    4 View Details [338..432] deduced N/A No confident structure predictions are available.
    5 View Details [433..537] deduced N/A Confident ab initio structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle