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Protein Overview: hpt1

General Information:
Name(s) found: hpt1 / SPAC23C11.13c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • xanthine phosphoribosyltransferase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 206 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: purine nucleotide salvage [ISSLink to PubMed article]
    nucleoside metabolic process [IEA]
    Molecular Function: hypoxanthine phosphoribosyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPVRLYYSY NDIHKMCAQQ AEKILETFRP DVIIAIGGGG FIPARILRTF LKKKGSKNIP  60
   61 IQAIGLSLYE ELVSDSPEEV PGLEVKRTQW LDFSTLGMVD LVGKNILIVD EVDDTRTTLH 120
  121 YALRELQRDV AEQAKKLNRE GEKTTFGIFV VHNKVKPKNA QLDKEILDKY YFTGCNTPDC 180
  181 WIMYPWEAQD IEEHDSHVAK MGDLKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] PSI-BLAST 28.154902 Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity, transferring glycosyl groups
    		•  3.91023158228049 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  3.89356447922614 bayes_pls_golite062009
  • adenine phosphoribosyltransferase activity
    		•  3.83339863213875 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.53679639481311 bayes_pls_golite062009
  • uracil phosphoribosyltransferase activity
    		•  2.36237864658341 bayes_pls_golite062009
  • catalytic activity
    		•  2.30431811394775 bayes_pls_golite062009
  • transferase activity
    		•  2.03376808731027 bayes_pls_golite062009
  • amidophosphoribosyltransferase activity
    		•  1.51802880667162 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.18255665419929 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.749909396904601 bayes_pls_golite062009
  • purine binding
    		•  0.745430157183377 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.552133387792911 bayes_pls_golite062009
  • binding
    		•  0.535390228935555 bayes_pls_golite062009
  • DNA binding
    		•  0.439741935655503 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.396538943915776 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle