YRC Public Data Repository - Protein Structure Prediction

Protein:	hpt1
Organism:	Schizosaccharomyces pombe
Length:	206 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hpt1.

Description	E-value	Query Range	Subject Range
TILS_LISIN - Bifunctional protein TilS/HprT OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=tilS/hprT PE=3 ... TILS_LISIN - Bifunctional protein tilS/hprT OS=Listeria innocua GN=tilS/hprT PE=3 SV=1	142.0	[0..2]	[206..473]
gi\|224500330 - gi\|224500330\|ref\|ZP_03668679.1\| hypothetical protein LmonF1_11939 [Listeria monocytogenes Finland 19... gi\|224503461 - gi\|224503461\|ref\|ZP_03671768.1\| hypothetical protein LmonFR_13287 [Listeria monocytogenes FSL R2-561... gi\|126941298, gi... - gi\|254900996\|ref\|ZP_05260920.1\| hypothetical protein LmonJ_14318 [Listeria monocytogenes J0161], gi\|... gi\|254913936, gi... - gi\|254913936\|ref\|ZP_05263948.1\| hypothetical protein LmonJ2_14108 [Listeria monocytogenes J2818], gi... gi\|133733948, gi... - gi\|254938274\|ref\|ZP_05269971.1\| hypothetical protein LmonF6_14141 [Listeria monocytogenes F6900], gi... gi\|47014358, gi\|... - gi\|47097258\|ref\|ZP_00234818.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... TILS_LISMO - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) ... TILS_LISMO - Bifunctional protein tilS/hprT OS=Listeria monocytogenes GN=tilS/hprT PE=3 SV=1	140.0	[0..2]	[206..473]
TILS_LISMF - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tilS/hprT PE=...	140.0	[0..2]	[206..473]
gi\|226222848, gi... - gi\|226222848\|ref\|YP_002756955.1\| hypothetical protein Lm4b_00217 [Listeria monocytogenes Clip81459],... gi\|47018468, gi\|... - gi\|47093161\|ref\|ZP_00230936.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... gi\|21667249 - gi\|21667249\|gb\|AAM74001.1\|AF467001_2 YacA/HprT-like protein [Listeria monocytogenes] gi\|153200654, gi... - gi\|254933059\|ref\|ZP_05266418.1\| hypothetical protein LmonH_11532 [Listeria monocytogenes HPB2262], g...	140.0	[0..2]	[206..473]
gi\|111063462 - gi\|111063462\|gb\|EAT84582.1\| hypothetical protein SNOG_08306 [Phaeosphaeria nodorum SN15]	136.0	[0..3]	[201..2]
gi\|116098531, gi... - gi\|116333184\|ref\|YP_794711.1\| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus brevis A...	135.0	[0..2]	[206..4]
gi\|74490731, gi\|... - gi\|75761781\|ref\|ZP_00741717.1\| Hypoxanthine-guanine phosphoribosyltransferase [Bacillus thuringiensi... gi\|218895200, gi... - gi\|218895200\|ref\|YP_002443611.1\| hypoxanthine phosphoribosyltransferase [Bacillus cereus G9842], gi\|...	134.0	[0..2]	[206..5]
gi\|152022664, gi... - gi\|89202216\|ref\|ZP_01180944.1\| Hypoxanthine phosphoribosyl transferase [Bacillus cereus subsp. cytot...	133.0	[0..2]	[206..5]
gi\|45185160, gi\|... - gi\|45185160\|ref\|NP_982877.1\| ABL070Cp [Ashbya gossypii ATCC 10895], gi\|44980796\|gb\|AAS50701.1\| ABL07... gi\|44980796 - gi\|44980796\|gb\|AAS50701.1\| ABL070Cp [Ashbya gossypii ATCC 10895]	133.0	[0..5]	[204..6]
HPRT_ENTFA - Hypoxanthine-guanine phosphoribosyltransferase OS=Enterococcus faecalis GN=hpt PE=3 SV=1 gi\|227072597, gi... - gi\|227520049\|ref\|ZP_03950098.1\| hypoxanthine-guanine phosphoribosyltransferase [Enterococcus faecali... HPRT_ENTFA - Hypoxanthine-guanine phosphoribosyltransferase OS=Enterococcus faecalis (strain ATCC 700802 / V583) ... gi\|227174967, gi... - gi\|227555910\|ref\|ZP_03985957.1\| hypoxanthine-guanine phosphoribosyltransferase [Enterococcus faecali... gi\|238857927, gi... - gi\|238857927\|ref\|ZP_04648156.1\| hypoxanthine phosphoribosyltransferase [Enterococcus faecalis TUSoD ...	133.0	[0..2]	[206..5]

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Predicted Domain #1

Region A:
Residues: [1-206]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPVRLYYSY NDIHKMCAQQ AEKILETFRP DVIIAIGGGG FIPARILRTF LKKKGSKNIP  60
   61 IQAIGLSLYE ELVSDSPEEV PGLEVKRTQW LDFSTLGMVD LVGKNILIVD EVDDTRTTLH 120
  121 YALRELQRDV AEQAKKLNRE GEKTTFGIFV VHNKVKPKNA QLDKEILDKY YFTGCNTPDC 180
  181 WIMYPWEAQD IEEHDSHVAK MGDLKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.154902
Match:	1r3uA
Description:	Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	3.83339863213875	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
transferase activity	2.03376808731027	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.51802880667162	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.18255665419929	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
purine binding	0.745430157183377	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
binding	0.535390228935555	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: