Protein Overview: SPAC1F3.05

General Information:
Name(s) found:	SPAC1F3.05 [Sanger Pombe]
Description(s) found: Found 18 descriptions. SHOW ALL	adaptin [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	510 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] trans-Golgi network [ISS] cytosol [IDA] Golgi apparatus [IDA]
Biological Process:	intracellular protein transport [IC] Golgi to vacuole transport [ISS]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSQTLSKY IDKATDQFNL EPNLALNIEI ADLINEKKGN TPREAALLIL KRVNSANPTV  60
   61 SYLALHLLDI CVKNCGYPFH FQIASEEFLN GFVSRFPNHP ISRMNKIQSK MLEMLEEWNY 120
  121 MLCKNNRHRE DFSRIHDIRE LMAFRGYKFP AVDEDSIAVM KPNNSLRSAQ ELAREDLEAH 180
  181 KAKLQELLRR GTPMDLAEAN ALMKVIAGYD EENTEDYSAL AAADLESIRS KALRVKQFLV 240
  241 NQTVSLEEGT LADAVESLKV YQTKIARILR EENEDEYYVQ KLLSLNDLLI NVIEECSNSD 300
  301 LIHSGTNVVS SQPNVVESHV PPSSNDTKQE SSLIDLMKLT EEPAVPSPSL PTNVPANQSL 360
  361 SMLSSLSNSM SSTSNGALNS PSYSQAAIPN TNSSLTSILQ SDSLMISTQL TSVQKSSGFA 420
  421 SYSVQFSNCS LTWPVSEVVF QVAVVKSLKL QLLPHTGDAI IAPGKQNAAH EIMNITNIPA 480
  481 DASDLRIRWR VQWIIGTDHR VEQGESHLPL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..160]	PSI-BLAST	38.0	Hrs
2	View Details	[161..370]	PSI-BLAST	24.0	ADP-ribosylation factor binding protein Gga1
3	View Details	[371..510]	PSI-BLAST	28.39794	Gamma1-adaptin domain

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
clathrin binding	4.42433208284373	bayes_pls_golite062009
ADP-ribosylation factor binding	3.85762908083934	bayes_pls_golite062009
binding	2.32938736470587	bayes_pls_golite062009
protein binding	2.16467447169895	bayes_pls_golite062009
small conjugating protein binding	1.40018260535396	bayes_pls_golite062009
ubiquitin binding	1.32638202696551	bayes_pls_golite062009
phosphoinositide binding	0.87586037360588	bayes_pls_golite062009
phospholipid binding	0.84481265656013	bayes_pls_golite062009
nucleic acid binding	0.544430532077345	bayes_pls_golite062009
DNA binding	0.201426073572255	bayes_pls_golite062009
lipid binding	0.176990783274449	bayes_pls_golite062009
transcription regulator activity	0.169924567699487	bayes_pls_golite062009

2

Term	Confidence	Notes
clathrin binding	5.9355718186759	bayes_pls_golite062009
binding	2.19865242653132	bayes_pls_golite062009
protein binding	1.957004610117	bayes_pls_golite062009
phosphoinositide binding	1.69886980741044	bayes_pls_golite062009
phospholipid binding	1.35873451348399	bayes_pls_golite062009
lipid binding	0.681936854618139	bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding	0.2359206178887	bayes_pls_golite062009
phosphatidylinositol binding	0.10007172207713	bayes_pls_golite062009

3

Term	Confidence	Notes
binding	1.77203848422196	bayes_pls_golite062009
protein binding	1.57801165255065	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle