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Protein Overview: hem14

General Information:
Name(s) found: hem14 / SPAC1F5.07c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • protoporphyrinogen oxidase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mitochondrion [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: heme biosynthetic process [ISSLink to PubMed article]
    Molecular Function: oxygen-dependent protoporphyrinogen oxidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIAICGGGI AGLSTAFYLA RLIPKCTIDL YEKGPRLGGW LQSVKIPCAD SPTGTVLFEQ  60
   61 GPRTLRPAGV AGLANLDLIS KLGIEDKLLR ISSNSPSAKN RYIYYPDRLN EIPSSILGSI 120
  121 KSIMQPALRP MPLAMMLEPF RKSKRDSTDE SVGSFMRRRF GKNVTDRVMS AMINGIYAGD 180
  181 LNDLSMHSSM FGFLAKIEKK YGNITLGLIR ALLAREILSP AEKALKAALL AEPKTAELSN 240
  241 SMKSTSMFAF KEGIETITLS IADELKKMPN VKIHLNKPAK TLVPHKTQSL VDVNGQAYEY 300
  301 VVFANSSRNL ENLISCPKME TPTSSVYVVN VYYKDPNVLP IRGFGLLIPS CTPNNPNHVL 360
  361 GIVFDSEQNN PENGSKVTVM MGGSAYTKNT SLIPTNPEEA VNNALKALQH TLKISSKPTL 420
  421 TNATLQQNCI PQYRVGHQDN LNSLKSWIEK NMGGRILLTG SWYNGVSIGD CIMNGHSTAR 480
  481 KLASLMNSSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..490] PSI-BLAST 46.154902 Crystal Structure of Protoporphyrinogen IX Oxidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on NADH or NADPH
    		•  5.26950448055146 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.2944515778721 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  1.3578742399915 bayes_pls_golite062009
  • binding
    		•  1.26657667590853 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  1.20561532241252 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.07656675953489 bayes_pls_golite062009
  • catalytic activity
    		•  1.03127962968326 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  0.945028138297487 bayes_pls_golite062009
  • transporter activity
    		•  0.890824576391732 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.706117386114413 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.705416796630992 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  0.575252508985992 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.491481205015383 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.386071802386842 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.284200164472054 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.26114823844682 bayes_pls_golite062009
  • DNA binding
    		•  0.175069486065946 bayes_pls_golite062009
  • ferrous iron binding
    		•  0.166200528859874 bayes_pls_golite062009
  • protein binding
    		•  0.0281459437915129 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.47

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle