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View Structure Prediction Details

Protein: hem14
Organism: Schizosaccharomyces pombe
Length: 490 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hem14.

Description E-value Query
Range
Subject
Range
gi|93117610 - gi|93117610|gb|ABE99707.1| phytoene desaturase [Nicotiana benthamiana]
209.0 [0..1] [487..111]
gi|152023392, gi... - gi|89201716|ref|ZP_01180452.1| Protoporphyrinogen oxidase [Bacillus cereus subsp. cytotoxis NVH 391-...
209.0 [0..2] [489..4]
CRTI_NARPS - Phytoene dehydrogenase, chloroplastic/chromoplastic OS=Narcissus pseudonarcissus GN=PDS1 PE=1 SV=1
208.0 [0..1] [487..98]
gi|42572897 - gi|42572897|ref|NP_974545.1| PDS3 (PHYTOENE DESATURASE 3); phytoene dehydrogenase [Arabidopsis thali...
208.0 [0..1] [490..93]
gi|193795408, gi... - gi|193795408|gb|ACF21784.1| phytoene desaturase [Gentiana lutea], gi|18146805|dbj|BAB82461.1| phytoe...
208.0 [0..1] [487..108]
gi|60672631 - gi|60672631|gb|AAX33347.1| phytoene desaturase [Prunus armeniaca]
208.0 [0..1] [487..102]
gi|13991882 - gi|13991882|gb|AAK51545.1| phytoene desaturase [Citrus x paradisi]
207.0 [0..1] [486..81]
gi|40456031 - gi|40456031|gb|AAR86105.1| phytoene desaturase [Momordica charantia var. abbreviata]
206.0 [0..1] [487..105]

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Predicted Domain #1
Region A:
Residues: [1-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIAICGGGI AGLSTAFYLA RLIPKCTIDL YEKGPRLGGW LQSVKIPCAD SPTGTVLFEQ  60
   61 GPRTLRPAGV AGLANLDLIS KLGIEDKLLR ISSNSPSAKN RYIYYPDRLN EIPSSILGSI 120
  121 KSIMQPALRP MPLAMMLEPF RKSKRDSTDE SVGSFMRRRF GKNVTDRVMS AMINGIYAGD 180
  181 LNDLSMHSSM FGFLAKIEKK YGNITLGLIR ALLAREILSP AEKALKAALL AEPKTAELSN 240
  241 SMKSTSMFAF KEGIETITLS IADELKKMPN VKIHLNKPAK TLVPHKTQSL VDVNGQAYEY 300
  301 VVFANSSRNL ENLISCPKME TPTSSVYVVN VYYKDPNVLP IRGFGLLIPS CTPNNPNHVL 360
  361 GIVFDSEQNN PENGSKVTVM MGGSAYTKNT SLIPTNPEEA VNNALKALQH TLKISSKPTL 420
  421 TNATLQQNCI PQYRVGHQDN LNSLKSWIEK NMGGRILLTG SWYNGVSIGD CIMNGHSTAR 480
  481 KLASLMNSSS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1sezA
Description: Crystal Structure of Protoporphyrinogen IX Oxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on NADH or NADPH 5.26950448055146 bayes_pls_golite062009
oxidoreductase activity 2.2944515778721 bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity 1.3578742399915 bayes_pls_golite062009
binding 1.26657667590853 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 1.20561532241252 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.07656675953489 bayes_pls_golite062009
catalytic activity 1.03127962968326 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 0.945028138297487 bayes_pls_golite062009
transporter activity 0.890824576391732 bayes_pls_golite062009
transmembrane transporter activity 0.706117386114413 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.705416796630992 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 0.575252508985992 bayes_pls_golite062009
substrate-specific transporter activity 0.491481205015383 bayes_pls_golite062009
nucleic acid binding 0.386071802386842 bayes_pls_golite062009
transcription regulator activity 0.284200164472054 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.26114823844682 bayes_pls_golite062009
DNA binding 0.175069486065946 bayes_pls_golite062009
ferrous iron binding 0.166200528859874 bayes_pls_golite062009
protein binding 0.0281459437915129 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle