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Protein Overview: cip2

General Information:
Name(s) found: cip2 / SPAC12G12.03 [Sanger Pombe]
Description(s) found:
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  • pir||S62534 hypothetical protein SPAC12G12.3 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19113807|ref|NP_592895.1| RNA-binding protein Cip2 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1351627|sp|Q09868.1|CIP2_SCHPO RecName: Full=RNA-binding post-transcriptional regulator cip2; AltName: Full=Csx1-interacting protein 2 [NCBI NR]
  • gi|1052521|emb|CAA91498.1| RNA-binding protein Cip2 [Schizosaccharomyces pombe] [NCBI NR]
  • RNA-binding protein Cip2 [Sanger Pombe]
  • (Q09868) Hypothetical RNA-binding protein C12G12.03 in chromosome I [Swiss-Prot]
  • RNA-binding post-transcriptional regulator cip2 OS=Schizosaccharomyces pombe GN=cip2 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE RNA-BINDING PROTEIN; SUBCELLULAR LOCALIZATION OF GFP FUSION- CYTOPLASM: Q09868; [pompepVF.fasta]
  • PUTATIVE RNA BINDING PROTEIN; SUBCELLULAR LOCALIZATION OF GFP FUSION- CYTOPLASM: Q09868; [pompepV13]
  • Hypothetical RNA-binding protein C12G12.03 in chromosome I [pompep4896]
  • |||RNA-binding protein [pompepnew.fasta]
  • |||RNA-binding protein|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|1052521|emb|CAA91498.1| SPAC12G12.03 [Schizosaccharomyces pombe]gi|2130262|pir||S62534 hypothetical protein SPAC12G12.3 - fission yeast (Schizosaccharomyces pombe)gi|1351627|sp|Q09868|YAG3_SCHPO Hypot [nrdb_11152004_Chlamydomonas]
  • |cip2||RNA-binding protein Cip2|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC12G12.03 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC12G12.03 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • RNA-binding post-transcriptional regulator cip2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cip2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of mRNA stability involved in response to stress [IMPLink to PubMed article]
    cellular response to oxidative stress [IGILink to PubMed article]
    Molecular Function: RNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGTSQRPL TPLSQAFLST NTLSPASSPL TFHSEAASLR RKRSNFFPKL DELNGAQDEE  60
   61 MRGLNIPGGS GYLENRYGRD KFTFSDAAVN SAGMGGSGIF SHNNADDGLG DGSSTVLPSS 120
  121 LKQMLDPEIS TANNPSAKPR RTRLQTAWKE ATNSAGLSLR SASALDVLKN SGPATTSLLS 180
  181 STTYPFDSLN AFNEPSHSHV PNSASSTALS RGMSNSVTLT APPEPDEETI PTAIVIKNIP 240
  241 FSLKKEVLFK VFTALDIPRP YAFNYHFDNG VFRGLAFANF HSPEEAKTVV QVLNGYEITG 300
  301 RRLRVEWKRQ LPPAERERVE RGKQEKRAVE ERKNQLKSPF SVANIGAGID FDLNDPAILN 360
  361 VYSHILLFYY RSDNTNDLVF DSSTTQEERR VAALLASRLN LNHSVTGDGE AKQVVITMPS 420
  421 THFTPANNSS ANHSPLMAPN ASTLNPSSLG ASNLSQPSLA NHLSSSGLFD NGLFSSGGLS 480
  481 SNFSSLRRPA PSMHLADSIR SLRGLNDSKA FSDIRSMPAT PLELATPFAN LNVSSPLDRN 540
  541 ATNSSNTLNG SAMNDYFASL TPSNTGAIGS RTFTKN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] MSA 4.296997 View MSA. No confident structure predictions are available.
    2 View Details [127..221] PSI-BLAST 32.39794 Poly(A)-binding protein
    3 View Details [222..433] PSI-BLAST 40.522879 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    4 View Details [434..576] PSI-BLAST 4.522879 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  4.63987691433124 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.05055109233024 bayes_pls_golite062009
  • mRNA binding
    		•  3.54495985180603 bayes_pls_golite062009
  • binding
    		•  3.00411894202318 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
    		• 1.35163561991147 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.884269546056316 bayes_pls_golite062009
  • DNA binding
    		•  0.841333741555926 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.599389001184667 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.544292786424842 bayes_pls_golite062009
  • transcription factor activity
    		•  0.182209144070426 bayes_pls_golite062009
    3
    Term Confidence Notes
  • RNA binding
    		•  4.63987691433124 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.05055109233024 bayes_pls_golite062009
  • mRNA binding
    		•  3.54495985180603 bayes_pls_golite062009
  • binding
    		•  3.00411894202318 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
    		• 1.35163561991147 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.884269546056316 bayes_pls_golite062009
  • DNA binding
    		•  0.841333741555926 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.599389001184667 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.544292786424842 bayes_pls_golite062009
  • transcription factor activity
    		•  0.182209144070426 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle