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Protein Overview: gef1

General Information:
Name(s) found: gef1 / SPAC24H6.09 [Sanger Pombe]
Description(s) found:
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  • gi|984706|emb|CAA90853.1| RhoGEF Gef1 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||S62411 probable guanine nucleotide exchange factor with coiled-coil regions - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19113855|ref|NP_592943.1| RhoGEF Gef1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1175438|sp|Q09763.1|GEF1_SCHPO RecName: Full=Rho guanine nucleotide exchange factor gef1 [NCBI NR]
  • RhoGEF Gef1 [Sanger Pombe]
  • (Q09763) Hypothetical protein C24H6.09 in chromosome I [Swiss-Prot]
  • Rho guanine nucleotide exchange factor gef1 OS=Schizosaccharomyces pombe GN=gef1 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE GUANINE NUCLEOTIDE EXCHANGE FACTOR; COILED-COIL REGIONS; PREDICTED COILED-COIL REGION: Q09763; [pompepVF.fasta]
  • PUTATIVE GUANINE NUCLEOTIDE EXCHANGE FACTOR WITH COILED-COIL REGIONS: Q09763; [pompepV13]
  • Hypothetical protein C24H6.09 in chromosome I [pompep4896]
  • |gef1||RhoGEF [pompepnew.fasta]
  • |gef1||RhoGEF|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative guanine nucleotide exchange factor with coiled-coil regions [Schizosaccharomyces pombe]gi|984706|emb|CAA90853.1| SPAC24H6.09 [Schizosaccharomyces pombe]gi|1175438|sp|Q09763|YA79_SCHPO Hypothetical protein C24H6.09 in chromosome Igi|2130365|pir [nrdb_11152004_Chlamydomonas]
  • |gef1||RhoGEF Gef1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC24H6.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC24H6.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Rho guanine nucleotide exchange factor gef1 [nr-271106-contam.fasta]
  • Rho guanine nucleotide exchange factor gef1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gef1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 753 amino acids

    Gene Ontology:
    Cellular Component: cell septum [IDALink to PubMed article]
    cell division site [IDALink to PubMed articleLink to PubMed article]
    medial cortex [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    regulation of establishment or maintenance of cell polarity [IGILink to PubMed article]
    regulation of barrier septum formation [IMPLink to PubMed article]
    establishment or maintenance of cell polarity [IGILink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    regulation of bipolar cell growth [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    Rho guanyl-nucleotide exchange factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METLKADLSD MSDSPEYFET LANRDLPRLP GTSKLHRAAC IKRKSINLSL PSNSYSLSYR  60
   61 QSDDTDGDVS ESQSEYRLSS GRRSRASFAR ALQDPQTPNT PPVSSQHRRF FSEGSFNLPN 120
  121 SNMSHSLNGD STASNSSTLT PNRIYGDRNR QDYAQSSRYT LPSLPSSPSY NCPTTLRKIH 180
  181 TNTSSNGTSR RVSGLGSFMA QNSSETSSNR TSAYLPGSST DEQEKRSSVT LASMPSSHSS 240
  241 TASLLSPLDT TSFSTKLDST ILALETDESL SRTISYATTS LPSTPGKRLS KESLAMSEAS 300
  301 SINPEYKRIK KRANLIKELV TTEAAYLNDL IAIQQSYGLR VKECSALNPV DAQTVFGDIE 360
  361 SLLTFTVEFH SRLYQAGEGS WRVNLDTQLI DPLPCNLGLI FLESLSEIGQ IYTGYCNRQD 420
  421 SVFKIITKWR EKPATASWIM EGDKIVQKYT NAWDLGSLII KPLQRLLKYP LLLQKIIDVT 480
  481 PESSSERPDL VLSYQLLQEL ISGINQKQKP SHKRGSLSAS HKRDAAWSLL YKATSNKSRP 540
  541 TTTSTELKTD ARLNFQRQVL QDFRQRFAIL KALHATLETW YVTVHRGFSV FEKVLAELEG 600
  601 LSALEPEDKP VDTWRKYHLL AHMMTANLPS QIQTSLNSSI LNPITNILRV IQKVIQFIIS 660
  661 AEFVIPAQKL EAISTLVEKE FHSVVYHFIG IQRSLYENYA QGFLFLIPQD MRDSILEETQ 720
  721 DYAELVRAFE PMHYDDEVLL EELMKSVSLA ARV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] MSA 3.337995 View MSA. No confident structure predictions are available.
    2 View Details [134..203] deduced N/A No confident structure predictions are available.
    3 View Details [204..753] PSI-BLAST 70.221849 No description for 2pz1A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle