YRC Public Data Repository - Protein Structure Prediction

Protein:	gef1
Organism:	Schizosaccharomyces pombe
Length:	753 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gef1.

Description	E-value	Query Range	Subject Range
gi\|50511235 - gi\|50511235\|dbj\|BAD32603.1\| mKIAA1998 protein [Mus musculus]	288.0	[0..36]	[699..588]
gi\|114599696 - gi\|114599696\|ref\|XP_517706.2\| PREDICTED: similar to Rho-guanine nucleotide exchange factor isoform 4...	283.0	[0..8]	[700..518]
gi\|113416642 - gi\|113416642\|ref\|XP_938042.2\| PREDICTED: similar to Rho-guanine nucleotide exchange factor (Rho-inte...	281.0	[0..8]	[700..518]
gi\|109077578 - gi\|109077578\|ref\|XP_001101425.1\| PREDICTED: similar to Rho-guanine nucleotide exchange factor (Rho-i...	279.0	[0..8]	[700..518]
gi\|109464298 - gi\|109464298\|ref\|XP_342180.3\| PREDICTED: similar to Rho-guanine nucleotide exchange factor (Rho-inte...	279.0	[0..36]	[699..723]

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Predicted Domain #1

Region A:
Residues: [1-133]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METLKADLSD MSDSPEYFET LANRDLPRLP GTSKLHRAAC IKRKSINLSL PSNSYSLSYR  60
   61 QSDDTDGDVS ESQSEYRLSS GRRSRASFAR ALQDPQTPNT PPVSSQHRRF FSEGSFNLPN 120
  121 SNMSHSLNGD STA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [134-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSSTLTPNR IYGDRNRQDY AQSSRYTLPS LPSSPSYNCP TTLRKIHTNT SSNGTSRRVS  60
   61 GLGSFMAQNS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [204-753]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SETSSNRTSA YLPGSSTDEQ EKRSSVTLAS MPSSHSSTAS LLSPLDTTSF STKLDSTILA  60
   61 LETDESLSRT ISYATTSLPS TPGKRLSKES LAMSEASSIN PEYKRIKKRA NLIKELVTTE 120
  121 AAYLNDLIAI QQSYGLRVKE CSALNPVDAQ TVFGDIESLL TFTVEFHSRL YQAGEGSWRV 180
  181 NLDTQLIDPL PCNLGLIFLE SLSEIGQIYT GYCNRQDSVF KIITKWREKP ATASWIMEGD 240
  241 KIVQKYTNAW DLGSLIIKPL QRLLKYPLLL QKIIDVTPES SSERPDLVLS YQLLQELISG 300
  301 INQKQKPSHK RGSLSASHKR DAAWSLLYKA TSNKSRPTTT STELKTDARL NFQRQVLQDF 360
  361 RQRFAILKAL HATLETWYVT VHRGFSVFEK VLAELEGLSA LEPEDKPVDT WRKYHLLAHM 420
  421 MTANLPSQIQ TSLNSSILNP ITNILRVIQK VIQFIISAEF VIPAQKLEAI STLVEKEFHS 480
  481 VVYHFIGIQR SLYENYAQGF LFLIPQDMRD SILEETQDYA ELVRAFEPMH YDDEVLLEEL 540
  541 MKSVSLAARV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.221849
Match:	2pz1A
Description:	No description for 2pz1A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits