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Protein Overview: pol4

General Information:
Name(s) found: pol4 / SPAC2F7.06c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • DNA polymerase X family [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 506 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: DNA replication [IEA]
    base-excision repair, gap-filling [TASLink to PubMed article]
    double-strand break repair via nonhomologous end joining [TASLink to PubMed article]
    [NOT]mating type switching [IMPLink to PubMed article]
    Molecular Function: nucleotide binding [TASLink to PubMed article]
    magnesium ion binding [IEA]
    [NOT]3'-5' exonuclease activity [IDALink to PubMed article]
    DNA binding [IEA]
    DNA-directed DNA polymerase activity [IDALink to PubMed article]
    5'-deoxyribose-5-phosphate lyase activity [IDALink to PubMed article]
    DNA-directed RNA polymerase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILASSTNY VLHNRLSNSQ YEDARSKIVN FGGEFTNDAA KADYIFVNYS QINRVRRELR  60
   61 TIGTPLETCV SCKLIVKIDW LNEPKESLTP GNPYVIWHRK PEMKVGSPYT PSTRPASHTE 120
  121 APNDFENHET PNTENNNEVK SIDNVDQEGS VYPTTKEYPY VLEIPRYACQ RKTPLKCVNQ 180
  181 AFVNALSVLK TCREVNGESV RTRAYGMAIA TIKAFPLPID SAEQLEKMPG CGPKIVHLWK 240
  241 EFASTGTLKE AEEFQKDPAS KILLLFYNIF GVGASHAAEW YQKGWRTIEQ VRKHKDSFTK 300
  301 QIKVGLEFYE DFCKTVTIEE ATEIYETIVS RMPDGIKIQS CLVGGFRRGK PVGADVDMVL 360
  361 SPSHTHSTKH LVDVLLRILD EEFQFRLISV QEHSCGGKKG YVMLAVILSN SSKINRRVDI 420
  421 IVVPPAYIGS AVLGWSGGIF FLRDLKLYAN SHLGLSYDSF EIINLKTGKD ICPDEFNEWK 480
  481 DPVEAEKDIF RYFSLEYIEP KFRNTG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..175] PSI-BLAST 16.30103 No description for 2dunA was found.
    2 View Details [176..506] PSI-BLAST 113.0 Terminal deoxynucleotidyl transferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA-directed DNA polymerase activity
    		•  5.14301767080098 bayes_pls_golite062009
  • DNA polymerase activity
    		•  5.09523809908438 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  2.75404349131504 bayes_pls_golite062009
  • catalytic activity
    		•  0.60409960326459 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle