Protein Overview: skb1

General Information:
Name(s) found:	skb1 / SPBC16H5.11c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T39614 kinase-binding protein 1 - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|2956763\|emb\|CAA17909.1\| type II protein arginine N-methyltransferase Skb1 [Schizosaccharomyces pombe] [NCBI NR] gi\|19112728\|ref\|NP_595936.1\| arginine N-methyltransferase Skb1 [Schizosaccharomyces pombe 972h-] [NCBI NR] gi\|12644354\|sp\|P78963.2\|SKB1_SCHPO RecName: Full=Protein arginine N-methyltransferase skb1; AltName: Full=Shk1 kinase-binding protein 1 [NCBI NR] type II protein arginine N-methyltransferase Skb1 [Sanger Pombe] Protein arginine N-methyltransferase skb1 OS=Schizosaccharomyces pombe GN=skb1 PE=2 SV=2 [Swiss-Prot] SHK1P KINASE-BINDING PROTEIN; REGULATION OF CELL MORPHOGENESIS; REGULATION OF MITOSIS; PROTEIN METHYLTRANSFERASE: O42946;P78963; [pompepVF.fasta] Protein arginine N-methyltransferase skb1 (EC 2.1.1.-) (Shk1 kinase-binding protein 1) [pompep4896] \|skb1\|\|protein methyltransferase (PMID 11278267) [pompepnew.fasta] \|skb1\|\|methyltransferase (PMID 11278267)\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] kinase-binding protein 1 [Schizosaccharomyces pombe]gi\|2956763\|emb\|CAA17909.1\| skb1 [Schizosaccharomyces pombe]gi\|12644354\|sp\|P78963\|SKB1_SCHPO Protein arginine N-methyltransferase skb1 (Shk1 kinase-binding protein 1)gi\|7492122\|pir\|\|T39614 kinase-bindi [nrdb_11152004_Chlamydomonas] \|skb1\|\|Shk1 kinase-binding protein 1\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] (P78963) Protein arginine N-methyltransferase skb1 (EC 2.1.1.-) (Shk1 kinase-binding protein 1) [pompep4896_normal_reversed] \|skb1\|rmt5\|type II protein arginine N-methyltransferase Skb1\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Protein arginine N-methyltransferase skb1 (Shk1 kinase-binding protein 1) [nr-271106-contam.fasta] SPBC16H5.11c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPBC16H5.11c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] Protein arginine N-methyltransferase skb1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=skb1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	645 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cell tip [IDA] cell cortex [IDA]
Biological Process:	regulation of response to osmotic stress [IMP] unidimensional cell growth [IGI] establishment or maintenance of cell polarity [IGI] negative regulation of mitotic cell cycle [IGI] peptidyl-arginine N-methylation [IC] cellular protein localization [IGI]
Molecular Function:	protein binding [IPI ] protein-arginine N-methyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRDGRIPQ YSIYPLPVPP MNSKTPTLGI VCSEGTISLS LEEGFEFVGV PLSGEGLKLR  60
   61 VEALAPSERL QEFLDDEVAY HPEENVHKVV GLSSAWLELD SEDTLIADRS EEVLLKEASY 120
  121 ASYCGLSSII LNGPTSPMNV MRYARAVSSA LNSTMNLKFL VQLAIESGHE DYFETWKMWD 180
  181 TIRSACGYHP RLKVALELPP ACSPPIELVN RWYAEPIEMI TMSCMAFVPN PNGYPVLGRK 240
  241 LRAIYALYLR LNPRILLWDN DAPEKIGDSP DYSIYMKHLF DSQPPAPLVE DLADSYKDYL 300
  301 QVPLQPLSYN LENITYEIFE RDPVKYAQYE QAIFSALMDR DESSVTRIAV VGAGRGPLVD 360
  361 CALRAAISSS RTVDMIALEK NPNAFSMLLM RNRQDWAGKV TLVFGDMRTW NPDYKIDILV 420
  421 SELLGSMGDN ELSPECLDGV QHVLDEETGI CIPSSYISYV TPIMSPKLWS EARNMNDPNA 480
  481 FERQYVVLMN SFDFLAADDE FRFQSLWSFH HPNKDSEVYT KNLHNKRFAS VRFQASSPGI 540
  541 LHGFAGYFEA TLYKDISLSI MPATMEAKSP DMFSWFPIYM PIKKPMYVPE NSQLEFHMWR 600
  601 LTDGMRVWFE WCANAYLVLR NGSQIKLSST EVHNISGKAF SCNMY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
protein-arginine N-methyltransferase activity	5.52520020727046	bayes_pls_golite062009
arginine N-methyltransferase activity	5.52520020727046	bayes_pls_golite062009
protein methyltransferase activity	5.03267617653315	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	4.4632173842967	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	4.42061797259061	bayes_pls_golite062009
histone methyltransferase activity	4.40911163698179	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	4.39379274790202	bayes_pls_golite062009
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
N-methyltransferase activity	4.07806017452628	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	3.55785970363721	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	2.86617323549909	bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity	2.80855981068149	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
DNA-methyltransferase activity	2.18991764495147	bayes_pls_golite062009
RNA methyltransferase activity	1.86200407013263	bayes_pls_golite062009
rRNA methyltransferase activity	1.79395300104934	bayes_pls_golite062009
histone methyltransferase activity (H2A-R3 specific)	1.49229188826344	bayes_pls_golite062009
[myelin basic protein]-arginine N-methyltransferase activity	1.49229188826344	bayes_pls_golite062009
histone methyltransferase activity (H3-R2 specific)	1.49229188826344	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
RNA binding	1.10729923226801	bayes_pls_golite062009
binding	0.976078016260105	bayes_pls_golite062009
histone binding	0.964746527369069	bayes_pls_golite062009
transcription regulator activity	0.914549843668268	bayes_pls_golite062009
tRNA methyltransferase activity	0.868107614027708	bayes_pls_golite062009
DNA binding	0.86027591375666	bayes_pls_golite062009
lysine N-methyltransferase activity	0.858129308056814	bayes_pls_golite062009
protein-lysine N-methyltransferase activity	0.858129308056814	bayes_pls_golite062009
histone-lysine N-methyltransferase activity	0.858129308056814	bayes_pls_golite062009
mRNA methyltransferase activity	0.73490663449605	bayes_pls_golite062009
mRNA (guanine-N7-)-methyltransferase activity	0.73490663449605	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
nucleic acid binding	0.616949327277483	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.102141401712309	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.0251895714734512	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..70]	deduced	N/A	No confident structure predictions are available.
2	View Details	[71..281]	MSA	1.314976	View MSA. No confident structure predictions are available.
3	View Details	[282..645]	PSI-BLAST	73.0	Structure of the Predominant Protein Arginine Methyltransferase PRMT1

Protein Overview: skb1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: