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Protein Overview: skb1

General Information:
Name(s) found: skb1 / SPBC16H5.11c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • type II protein arginine N-methyltransferase Skb1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 645 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    cell cortex [IDALink to PubMed article]
    Biological Process: regulation of response to osmotic stress [IMPLink to PubMed article]
    unidimensional cell growth [IGILink to PubMed article]
    establishment or maintenance of cell polarity [IGILink to PubMed article]
    negative regulation of mitotic cell cycle [IGILink to PubMed article]
    peptidyl-arginine N-methylation [ICLink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed articleLink to PubMed articleLink to PubMed article]
    protein-arginine N-methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRDGRIPQ YSIYPLPVPP MNSKTPTLGI VCSEGTISLS LEEGFEFVGV PLSGEGLKLR  60
   61 VEALAPSERL QEFLDDEVAY HPEENVHKVV GLSSAWLELD SEDTLIADRS EEVLLKEASY 120
  121 ASYCGLSSII LNGPTSPMNV MRYARAVSSA LNSTMNLKFL VQLAIESGHE DYFETWKMWD 180
  181 TIRSACGYHP RLKVALELPP ACSPPIELVN RWYAEPIEMI TMSCMAFVPN PNGYPVLGRK 240
  241 LRAIYALYLR LNPRILLWDN DAPEKIGDSP DYSIYMKHLF DSQPPAPLVE DLADSYKDYL 300
  301 QVPLQPLSYN LENITYEIFE RDPVKYAQYE QAIFSALMDR DESSVTRIAV VGAGRGPLVD 360
  361 CALRAAISSS RTVDMIALEK NPNAFSMLLM RNRQDWAGKV TLVFGDMRTW NPDYKIDILV 420
  421 SELLGSMGDN ELSPECLDGV QHVLDEETGI CIPSSYISYV TPIMSPKLWS EARNMNDPNA 480
  481 FERQYVVLMN SFDFLAADDE FRFQSLWSFH HPNKDSEVYT KNLHNKRFAS VRFQASSPGI 540
  541 LHGFAGYFEA TLYKDISLSI MPATMEAKSP DMFSWFPIYM PIKKPMYVPE NSQLEFHMWR 600
  601 LTDGMRVWFE WCANAYLVLR NGSQIKLSST EVHNISGKAF SCNMY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] deduced N/A No confident structure predictions are available.
    2 View Details [71..281] MSA 1.314976 View MSA. No confident structure predictions are available.
    3 View Details [282..645] PSI-BLAST 73.0 Structure of the Predominant Protein Arginine Methyltransferase PRMT1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein-arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  5.03267617653315 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  4.4632173842967 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  4.42061797259061 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  4.40911163698179 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  4.39379274790202 bayes_pls_golite062009
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  3.55785970363721 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.86617323549909 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  2.80855981068149 bayes_pls_golite062009
  • transferase activity
    		•  2.22303238506686 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.18991764495147 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  1.86200407013263 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  1.79395300104934 bayes_pls_golite062009
  • histone methyltransferase activity (H2A-R3 specific)
    		•  1.49229188826344 bayes_pls_golite062009
  • [myelin basic protein]-arginine N-methyltransferase activity
    		•  1.49229188826344 bayes_pls_golite062009
  • histone methyltransferase activity (H3-R2 specific)
    		•  1.49229188826344 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • RNA binding
    		•  1.10729923226801 bayes_pls_golite062009
  • binding
    		•  0.976078016260105 bayes_pls_golite062009
  • histone binding
    		•  0.964746527369069 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  0.868107614027708 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • mRNA methyltransferase activity
    		•  0.73490663449605 bayes_pls_golite062009
  • mRNA (guanine-N7-)-methyltransferase activity
    		•  0.73490663449605 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.102141401712309 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.0251895714734512 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle