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Protein Overview: upf1

General Information:
Name(s) found: upf1 / SPAC16C9.06c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • ATP-dependent RNA helicase Upf1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 925 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: translational termination [ISS]
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [ISSLink to PubMed article]
    Molecular Function: ATP binding [ICLink to PubMed article]
    DNA binding [IEA]
    zinc ion binding [IEA]
    ATP-dependent RNA helicase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLGLQPNND ISSLVSSKNM TSENGLEHQF EELLVEKQYS EEHCAYCHIK NPNSILKCLH  60
   61 CNKWFCNVRG KSGASHIISH LVRARHKQVA LHSHSSLSDT VLECYNCGTR NVFLLGFIPA 120
  121 KAKTVVVLLC RQPCARASIA KDMNWDLTQW QPIISDRQFL PWLITPPSEE EQKLAIPITS 180
  181 QQMVRLEELW RKDPNANLED LDKPIEDDSL PSVELRYKDA HAYQAVLSPL IQAEADYDKR 240
  241 LKESQTQKDV VVRWDQAINK RYTAWFLLPK LESGEIRLAI GDEMKLTYEG ELRAPWSSTG 300
  301 YVIKIPNNVS DEVGLELKRS DKVPIECTHN FSVDYVWKST SFDRMQTALR LFATDGSRLS 360
  361 SFLYHKLLGH DIPPSFLKPK LPSDLSVPNL PKLNASQSEA VRAVLSKPLS LIQGPPGTGK 420
  421 TVTSASVVYH LATMQSRKRK SHSPVLVCAP SNVAVDQLAE KIHRTGLRVV RVAAKSREDI 480
  481 ESSVSFLSLH EQIKNYKFNP ELQRLLKLRS ENNELSIQDE KKLRILVAAA EKELLRAAHV 540
  541 ICCTCVGAGD RRISKYKFRS VLIDEATQAS EPECMIPLVL GAKQVVLVGD HQQLGPVVMN 600
  601 KKVALASLSQ SLFERLIILG NSPFRLVVQY RMHPCLSEFP SNTFYEGTLQ NGVTTSERIA 660
  661 RHVDFPWIQP DSPLMFYANF GQEELSASGT SFLNRTEAST CEKIVTTFLR SNVLPEQIGI 720
  721 VTPYDGQRSY IVQYMQNNGS MQKDLYKAVE VASVDAFQGR EKDFIILSCV RSSEHQGIGF 780
  781 VNDPRRLNVA LTRAKYGVIV LGNPKVLAKH ALWYHFVLHC KEKGYLVEGT LNSLQKFSLT 840
  841 LTPPQKPQKF KRDLNVQRSL SPIQNAGSAM LPSFSNLPNL YSSSYLEEWN VFAQYKRRES 900
  901 NATDFEDFRS QVGDDESKFD EPTRF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 80.69897 No description for 2iykA was found.
    2 View Details [206..270] PSI-BLAST 138.0 No description for 2gjkA was found.
    3 View Details [271..390] FFAS03 1.11 No description for 2gjkA was found.
    4 View Details [391..515] PSI-BLAST 11.39794 DEXX box DNA helicase
    5 View Details [516..828] PSI-BLAST 36.154902 STRUCTURE OF DNA HELICASE WITH ADPNP
    6 View Details [829..925] PSI-BLAST 80.09691 No description for 2is1A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle