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View Structure Prediction Details

Protein: upf1
Organism: Schizosaccharomyces pombe
Length: 925 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for upf1.

Description E-value Query
Range
Subject
Range
gi|76620868 - gi|76620868|ref|XP_612154.2| PREDICTED: similar to regulator of nonsense transcripts 1 [Bos taurus]
854.0 [0..5] [901..82]
gi|73986070 - gi|73986070|ref|XP_533868.2| PREDICTED: similar to regulator of nonsense transcripts 1 [Canis famili...
854.0 [0..5] [901..85]
gi|3328175, gi|1... - gi|3328175|gb|AAC26788.1| nonsense-mediated mRNA decay trans-acting factor [Homo sapiens], gi|273935...
854.0 [0..5] [901..84]
gi|12836885, gi|... - gi|13507601|ref|NP_109605.1| regulator of nonsense transcripts 1 [Mus musculus], gi|12836885|gb|AAK0...
851.0 [0..5] [901..79]
gi|109504000, gi... - gi|149036014|gb|EDL90680.1| rCG38820 [Rattus norvegicus], gi|109504000|ref|XP_001070971.1| PREDICTED...
851.0 [0..5] [901..79]
gi|148223321, gi... - gi|49116641|gb|AAH73441.1| MGC80941 protein [Xenopus laevis], gi|148223321|ref|NP_001085862.1| MGC80...
850.0 [0..5] [895..63]

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Predicted Domain #1
Region A:
Residues: [1-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLGLQPNND ISSLVSSKNM TSENGLEHQF EELLVEKQYS EEHCAYCHIK NPNSILKCLH  60
   61 CNKWFCNVRG KSGASHIISH LVRARHKQVA LHSHSSLSDT VLECYNCGTR NVFLLGFIPA 120
  121 KAKTVVVLLC RQPCARASIA KDMNWDLTQW QPIISDRQFL PWLITPPSEE EQKLAIPITS 180
  181 QQMVRLEELW RKDPNANLED LDKPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.69897
Match: 2iykA
Description: No description for 2iykA was found.

Predicted Domain #2
Region A:
Residues: [206-270]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDDSLPSVEL RYKDAHAYQA VLSPLIQAEA DYDKRLKESQ TQKDVVVRWD QAINKRYTAW  60
   61 FLLPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 138.0
Match: 2gjkA
Description: No description for 2gjkA was found.

Predicted Domain #3
Region A:
Residues: [271-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LESGEIRLAI GDEMKLTYEG ELRAPWSSTG YVIKIPNNVS DEVGLELKRS DKVPIECTHN  60
   61 FSVDYVWKST SFDRMQTALR LFATDGSRLS SFLYHKLLGH DIPPSFLKPK LPSDLSVPNL 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.11
Match: 2gjkA
Description: No description for 2gjkA was found.

Predicted Domain #4
Region A:
Residues: [391-515]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKLNASQSEA VRAVLSKPLS LIQGPPGTGK TVTSASVVYH LATMQSRKRK SHSPVLVCAP  60
   61 SNVAVDQLAE KIHRTGLRVV RVAAKSREDI ESSVSFLSLH EQIKNYKFNP ELQRLLKLRS 120
  121 ENNEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.39794
Match: 1qhhA
Description: DEXX box DNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [516-828]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIQDEKKLRI LVAAAEKELL RAAHVICCTC VGAGDRRISK YKFRSVLIDE ATQASEPECM  60
   61 IPLVLGAKQV VLVGDHQQLG PVVMNKKVAL ASLSQSLFER LIILGNSPFR LVVQYRMHPC 120
  121 LSEFPSNTFY EGTLQNGVTT SERIARHVDF PWIQPDSPLM FYANFGQEEL SASGTSFLNR 180
  181 TEASTCEKIV TTFLRSNVLP EQIGIVTPYD GQRSYIVQYM QNNGSMQKDL YKAVEVASVD 240
  241 AFQGREKDFI ILSCVRSSEH QGIGFVNDPR RLNVALTRAK YGVIVLGNPK VLAKHALWYH 300
  301 FVLHCKEKGY LVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.154902
Match: 1qhhB
Description: STRUCTURE OF DNA HELICASE WITH ADPNP
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [829-925]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTLNSLQKFS LTLTPPQKPQ KFKRDLNVQR SLSPIQNAGS AMLPSFSNLP NLYSSSYLEE  60
   61 WNVFAQYKRR ESNATDFEDF RSQVGDDESK FDEPTRF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.09691
Match: 2is1A
Description: No description for 2is1A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle