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Protein Overview: rad3

General Information:
Name(s) found: rad3 / SPBC216.05 [Sanger Pombe]
Description(s) found:
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  • pir||T39911 rad3 checkpoint protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|4581506|emb|CAB40165.1| ATR checkpoint kinase Rad3 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112149|ref|NP_595357.1| ATR checkpoint kinase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|12644379|sp|Q02099.2|RAD3_SCHPO RecName: Full=Protein kinase rad3; AltName: Full=DNA repair protein rad3 [NCBI NR]
  • ATR checkpoint kinase [Sanger Pombe]
  • Protein kinase rad3 OS=Schizosaccharomyces pombe GN=rad3 PE=1 SV=2 [Swiss-Prot]
  • ATR (ATM) CHECKPOINT KINASE; SIMILAR TO S. CEREVISIAE MEC1: Q02099;Q92391;Q9UUM1; [pompepVF.fasta]
  • RAD3 CHECKPOINT PROTEIN: Q02099;Q92391;Q9UUM1; [pompepV13]
  • DNA repair protein rad3 [pompep4896]
  • |rad3||ATR (ATM) checkpoint kinase [pompepnew.fasta]
  • |rad3||ATR (ATM) checkpoint kinase|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • rad3 checkpoint protein [Schizosaccharomyces pombe]gi|4581506|emb|CAB40165.1| rad3 [Schizosaccharomyces pombe]gi|12644379|sp|Q02099|RAD3_SCHPO DNA repair protein rad3gi|7493255|pir||T39911 rad3 checkpoint protein - fission yeast (Schizosaccharomyces po [nrdb_11152004_Chlamydomonas]
  • |rad3||ATR checkpoint kinase|Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q02099) DNA repair protein rad3 [pompep4896_normal_reversed]
  • |rad3||ATR checkpoint kinase Rad3|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC216.05 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • ATR checkpoint kinase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Protein kinase rad3 (DNA-repair protein rad3) [nr-271106-contam.fasta]
  • Protein kinase rad3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rad3 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 2386 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromosome [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    protein complex [RCALink to PubMed article]
    Biological Process: reciprocal meiotic recombination [IMPLink to PubMed article]
    DNA replication [IEA]
    intra-S DNA damage checkpoint [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    protein serine/threonine kinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQHAKRKAG SLDLSPRGLD DRQAFGQLLK EVLALDKEHE LGRSNSLPSM TSELVEVLIE  60
   61 VGLLAFKHDD SKSEFISPKM LKEAHLSLQA LMLILKRSPT VLREIKSSVT LLDWILPRTI 120
  121 SLFADIRFIK LFDSLKEFHK LIYQLISEKS FLWDLYASFM RYWKYYITNV SSIVLQITNA 180
  181 TFPYKMPSPN SQPLQSITPN YPTHREDKFD LLIINIEEAC TFFFESAHFF AQCSYLKKSN 240
  241 FPSPPLFTAW TWIKPCFFNF VILLKRISIG DSQLFLHLHS RIVQTLCCFS LNFIYHGLPI 300
  301 CEKSKHILMS SINLTLGSLK KTYTVANTAI SLFFLSLFVL PKTVAGLFYP FGVSLLSDFK 360
  361 VLEQLEPDSD LKKAIILFKC RYQSSEIDQT TLRAFGEICT GKLENTLFSN SELNLFLLHY 420
  421 LSLDNDLSNI LKVDFQNGHN ICTFAKWCIN NNLDEPSNLK HFREMLDYYS SHNVTISEDD 480
  481 LKNFSLVLCT HVAKVNEKTN SIFRTYEVHG CEVCNSFCLL FDERSLFKIP YHELFCALLK 540
  541 NPDIISSSVK QSLLLDGFFR WSQHCSNFNK ESMLSLREFI MKALASTSRC LRVVAAKVLP 600
  601 IFIKGPNNLD IVEFHKESKA LIFNTLKILA VENTAILETV ILSWISLSRV VEEEELHFVL 660
  661 LEVISSVINS GIFYQGIGLS ALQQIASTRH ISVWQLLSPY WPTVSVAIVQ GMGKKPNIAS 720
  721 LFAQLMNISE GDFLIRTQAY TLPFLVLTKN KALIVRIAEL SQSDVATLCL TNMHKILASL 780
  781 LTTDHPNLEE SVMLLLSLAT SDFEKVDLTS LLRSDPISIT VELLQLYQND VPHEKIENAL 840
  841 RKVAMIVSQV VNDEDLSNKE LLYDFFNNHI LGILAEFSNI LNDLKGKTSI NEKIKTIVGI 900
  901 EKMLSLCGGA VKLGLPQILS NLQSAFQNEH LRFYAIKAWF SLILATKEPE YSSIAGLSLV 960
  961 ILPPLFPYLE PQEAELVIQI FDFISSDTHK CLQGLKWAIP TSLDSACFSL KAKEIFCSLQ1020
 1021 NEDFYSELQS IIKCLTNENE PVCYLGLQKL ELFFQAKVDE LHDTLNLDIS NEVLDQLLRC1080
 1081 LLDCCVKYAS TNMQISYLAA KNLGELGAID PSRAKAQHII KETVVLDNFE NGEESLKFIL1140
 1141 DFMQSQLIPA FLVTTDTKAQ GFLAYALQEF LKLGGFKSAV INKKKGLTVV TEHWMSLPDL1200
 1201 SKRVLIPFLT SKYHLTPIPK IDIRYPIYKE NVTIHTWMQL FSLKLMEYAH SQNAEKIFGI1260
 1261 CSKVVKDQEV NIPCFLLPFL VLNVILTESE LEVNKVIEEF QLVINQPGPD GLNSVGQQRY1320
 1321 TSFVDVFFKI VDYLNKWLRM RKKRNWDRRS AIARKENRYM SVEDATSRES SISKVESFLS1380
 1381 RFPSKTLGIV SLNCGFHARA LFYWEQHIRN ATAPYAALES DYRVLQEIYA GIDDPDEIEA1440
 1441 VSLNFHDYSF DQQLLLHENS GTWDSALSCY EIIIQKDPEN KKAKIGLLNS MLQSGHYESL1500
 1501 VLSLDSFIIN DNHEYSKMLN LGIEASWRSL SIDSLKKCLS KSNLESFEAK LGSIFYQYLR1560
 1561 KDSFAELTER LQPLYVDAAT AIANTGAHSA YDCYDILSKL HAINDFSRIA ETDGIVSDNL1620
 1621 DIVLRRRLSQ VAPYGKFKHQ ILSTHLVGYE KFENTKKTAE IYLEIARISR KNGQFQRAFN1680
 1681 AILKAMDLDK PLATIEHAQW WWHQGQHRKA ISELNFSLNN NMFDLVDEHE ERPKNRKETL1740
 1741 GNPLKGKVFL KLTKWLGKAG QLGLKDLETY YHKAVEIYSE CENTHYYLGH HRVLMYEEEQ1800
 1801 KLPVNEQSER FLSGELVTRI INEFGRSLYY GTNHIYESMP KLLTLWLDFG AEELRLSKDD1860
 1861 GEKYFREHII SSRKKSLELM NSNVCRLSMK IPQYFFLVAL SQMISRVCHP NNKVYKILEH1920
 1921 IIANVVASYP GETLWQLMAT IKSTSQKRSL RGKSILNVLH SRKLSMSSKV DIKALSQSAI1980
 1981 LITEKLINLC NTRINSKSVK MSLKDHFRLS FDDPVDLVIP AKSFLDITLP AKDANRASHY2040
 2041 PFPKTQPTLL KFEDEVDIMN SLQKPRKVYV RGTDGNLYPF LCKPKDDLRK DARLMEFNNL2100
 2101 ICKILRKDQE ANRRNLCIRT YVVIPLNEEC GFIEWVNHTR PFREILLKSY RQKNIPISYQ2160
 2161 EIKVDLDFAL RSPNPGDIFE KKILPKFPPV FYEWFVESFP EPNNWVTSRQ NYCRTLAVMS2220
 2221 IVGYVLGLGD RHGENILFDE FTGEAIHVDF NCLFDKGLTF EKPEKVPFRL THNMVDAMGP2280
 2281 TGYEGGFRKA SEITMRLLRS NQDTLMSVLE SFLHDPLVEW NRKKSSSKYP NNEANEVLDI2340
 2341 IRKKFQGFMP GETIPLSIEG QIQELIKSAV NPKNLVEMYI GWAAYF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.32

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle