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Protein Overview: ade6

General Information:
Name(s) found: ade6 / SPCC1322.13 [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • phosphoribosylaminoimidazole carboxylase Ade6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 552 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: 'de novo' IMP biosynthetic process [ISSLink to PubMed article]
    purine base metabolic process [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    phosphoribosylaminoimidazole carboxylase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKQVVGIL GGGQLGRMMV EAAHRLNIKC IILDAANSPA KQIDGGREHI DASFTDPDAI  60
   61 VELSKKCTLL TTEIEHINTD ALAAVTKSVA VEPSPATLRC IQDKYLQKQH LQVFKIALPE 120
  121 FCDAPDQESV EKAGQEFGYP FVLKSKTLAY DGRGNYVVHQ PSEIPTAIKA LGDRPLYVEK 180
  181 FVPFSMEIAV MVVRSLDGKV YAYPTTETIQ KDNVCHLVYA PARLPFSIQQ RAQTLAMDAV 240
  241 RTFEGAGIYG VEMFVLQDGE TILLNEIAPR PHNSGHYTIE ACPTSQFEAH LRAICGLPFS 300
  301 EINTQLSTST THALMVNILG TDDPDYVSKI AKRSLSIPGA TLHLYGKAES RKGRKMGHVT 360
  361 IISDSPQECE RRYQMLLDVK DPVESPVVGI IMGSDSDLSK MKDAAVILDE FKVPYELTIV 420
  421 SAHRTPDRMV TYARTAASRG LRVIIAGAGG AAHLPGMVAA MTPLPVIGVP VKGSTLDGVD 480
  481 SLHSIVQMPR GVPVATVAIN NSQNAGILAC RILATFQPSL LAAMESFMDN MKEIVLEKAD 540
  541 KLEKVGWKNY SA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..394] PSI-BLAST 57.0 Crystal structure of Probable phosphoribosylglycinamide formyl transferase (PH0318) from Pyrococcus horikoshii OT3
    2 View Details [395..552] PSI-BLAST 40.69897 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphoribosylaminoimidazole carboxylase activity
    		•  12.126616405613 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  8.23768576957333 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  2.36590642968819 bayes_pls_golite062009
  • catalytic activity
    		•  1.94758748334979 bayes_pls_golite062009
  • lyase activity
    		•  0.685887227538264 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle