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Protein Overview: SPBC646.16

General Information:
Name(s) found: SPBC646.16 [Sanger Pombe]
Description(s) found:
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  • gi|7489941|pir||T40592 26s proteasome alpha subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|4160352|emb|CAA22820.1| 20S proteasome component alpha 1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112166|ref|NP_595374.1| 20S proteasome component alpha 1 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|12229906|sp|O94517.1|PSA6_SCHPO RecName: Full=Probable proteasome subunit alpha type-6 [NCBI NR]
  • 20S proteasome component alpha 1 [Sanger Pombe]
  • Probable proteasome subunit alpha type-6 OS=Schizosaccharomyces pombe GN=SPBC646.16 PE=2 SV=1 [Swiss-Prot]
  • 20S PROTEASOME COMPONENT (ALPHA 1): O94517; [pompepVF.fasta]
  • Probable proteasome subunit alpha type 6 (EC 3.4.25.1) [pompep4896]
  • |||20S proteasome component (alpha 1) [pompepnew.fasta]
  • |||20S proteasome component (alpha 1)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • 20S proteasome component (alpha 1) [Schizosaccharomyces pombe]gi|4160352|emb|CAA22820.1| 20S proteasome component (alpha 1); similar to S. cerevisiae YGL011C [Schizosaccharomyces pombe]gi|7489941|pir||T40592 26s proteasome alpha subunit - fission yeast [nrdb_11152004_Chlamydomonas]
  • |||20S proteasome component |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O94517) Probable proteasome subunit alpha type 6 (EC 3.4.25.1) [pompep4896_normal_reversed]
  • |||20S proteasome component alpha 1 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Probable proteasome subunit alpha type 6 [nr-271106-contam.fasta]
  • 20S proteasome subunit alpha 1 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC646.16 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Probable proteasome subunit alpha type-1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC646.16 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 244 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][NASLink to PubMed article]
    proteasome core complex, alpha-subunit complex [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [ISSLink to PubMed article]
    regulation of cell cycle [RCALink to PubMed article]
    mitotic cell cycle [IC]
    Molecular Function: endopeptidase activity [ISSLink to PubMed article]
    threonine-type endopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQARGFDRT ITVFSPEGRL YQVEYAFKAF NNAGITSVGV TGKNCACVIS QKKVPDKLID  60
   61 ASTVKHVFPI TKGIGCVMTG SIADARAQVS RARSEAAEFE YKNGYPMPCD VLAKRMANIA 120
  121 QVSTQRAAMR PLGVAMTLVA VDDEIGPSLF KLDPAGFYIG YKATSAGPKQ TETINWLEKR 180
  181 FKKDGIPSNL TDTVETGIQA LMSSLSTDFK STELQIGVVE DDKPFRVLSV EEIEAHLQSI 240
  241 AEKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] PSI-BLAST 68.522879 Proteasome alpha subunit (non-catalytic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • endopeptidase activity
    		•  6.91642761177919 bayes_pls_golite062009
  • peptidase activity
    		•  6.84511694091156 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  6.5973571808298 bayes_pls_golite062009
  • hydrolase activity
    		•  4.47652590304822 bayes_pls_golite062009
  • threonine-type endopeptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • threonine-type peptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • binding
    		•  1.75265921676176 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.39216781236247 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle