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Protein Overview: cwp1

General Information:
Name(s) found: cwp1 / SPAPB1A10.04c [Sanger Pombe]
Description(s) found:
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  • gi|3004489|emb|CAA11246.1| geranylgeranyl transferase type I [Schizosaccharomyces pombe] [NCBI NR]
  • gi|26397994|sp|O60052.1|FNTA_SCHPO RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; AltName: Full=CAAX farnesyltransferase subunit alpha; AltName: Full=Ras proteins prenyltransferase subunit alpha; AltName: Full=FT [NCBI NR]
  • gi|19114430|ref|NP_593518.1| geranylgeranyltransferase I alpha subunit Cwp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|12188968|emb|CAC21477.1| geranylgeranyltransferase I alpha subunit Cwp1 [Schizosaccharomyces pombe] [NCBI NR]
  • geranylgeranyltransferase I alpha subunit Cwp1 [Sanger Pombe]
  • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha - Schizosaccharomyces pombe (Fission yeast) [Swiss-Prot]
  • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha OS=Schizosaccharomyces pombe GN=cwp1 PE=1 SV=1 [Swiss-Prot]
  • GERANYLGERANYL TRANSFERASE TYPE I: O60052; [pompepVF.fasta]
  • Protein farnesyltransferase alpha subunit (EC 2.5.1.-) (CAAX farnesyltransferase alpha subunit) (RAS proteins prenyltransferase alpha) (FTase-alpha) [pompep4896]
  • |cwp1||geranylgeranyltransferase type I (GGTase I), alpha subunit (PMID 9781874) [pompepnew.fasta]
  • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) [4896.FASTAC]
  • |cwp1||geranylgeranyltransferase (alpha subunit) (PMID 9781874)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • geranylgeranyl transferase type i [Schizosaccharomyces pombe]gi|3004489|emb|CAA11246.1| geranylgeranyl transferase type I [Schizosaccharomyces pombe]gi|12188968|emb|CAC21477.1| cwp1 [Schizosaccharomyces pombe]gi|26397994|sp|O60052|PFTA_SCHPO Protein fa [nrdb_11152004_Chlamydomonas]
  • |cwp1||geranylgeranyltransferase I |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O60052) Protein farnesyltransferase alpha subunit (EC 2.5.1.-) (CAAX farnesyltransferase alpha subunit) (RAS proteins prenyltransferase alpha) (FTase-alpha) [pompep4896_normal_reversed]
  • |cwp1||geranylgeranyltransferase I alpha subunit Cwp1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAPB1A10.04c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • geranylgeranyl transferase type I [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAPB1A10.04c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha) [nr-271106-contam.fasta]
  • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cwp1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 294 amino acids

    Gene Ontology:
    Cellular Component: CAAX-protein geranylgeranyltransferase complex [NASLink to PubMed article]
    nucleus [IDALink to PubMed article]
    Biological Process: 1,3-beta-glucan biosynthetic process [IPILink to PubMed article]
    protein amino acid geranylgeranylation [ICLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    protein geranylgeranyltransferase activity [IDALink to PubMed article]
    protein farnesyltransferase activity [IEA]
    Rab geranylgeranyltransferase activity [IPILink to PubMed article]
    CAAX-protein geranylgeranyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPIDPELNE ILDFTEYGPL TPIPQDDGEN PLAKICYTTG YEQGMAYFRA IMAKKEYSLR  60
   61 ALNLTGFLIM NNPAHYTVWA YRFQILNHTP SYIDNELEWL DEIAEDFQKN YQVWHHRQKI 120
  121 LSLTKNYERE LEFTKKMFEI DSKNYHVWSY RVWILQNFND YSQELKLTNE LLEKDIYNNS 180
  181 AWNHRFYVLF ETSKVVSWSL EEELNYLKDK ILFAPDNQSA WNYLCGVLDK SGPSKLDNLI 240
  241 ANLRKNLPAL HKPLLEFLAM YEPSSSEEIY QKLANEVDVP HAALWTWMSQ RSNP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 16.39794 Protein farnesyltransferase alpha-subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein geranylgeranyltransferase activity
    		•  12.6759732522795 bayes_pls_golite062009
  • protein farnesyltransferase activity
    		•  12.1496415778348 bayes_pls_golite062009
  • prenyltransferase activity
    		•  11.9861287863026 bayes_pls_golite062009
  • CAAX-protein geranylgeranyltransferase activity
    		•  10.4593287273566 bayes_pls_golite062009
  • protein prenyltransferase activity
    		•  8.98854711542899 bayes_pls_golite062009
  • Rab geranylgeranyltransferase activity
    		•  6.64922604670914 bayes_pls_golite062009
  • binding
    		•  1.29714843812125 bayes_pls_golite062009
  • transferase activity
    		•  1.16403391633234 bayes_pls_golite062009
  • acetylcholine receptor regulator activity
    		•  1.13463233019211 bayes_pls_golite062009
  • catalytic activity
    		•  0.874200184943744 bayes_pls_golite062009
  • protein binding
    		•  0.439760416772506 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle