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Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate. Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein. Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein farnesyltransferase activity
Acc: GO:0004660
Aspect: Molecular Function
Desc: Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
Synonyms:
  • protein-cysteine farnesyltransferase activity
  • FTase activity
  • GO:0018223
  • CAAX farnesyltransferase activity
  • farnesyl-diphosphate:protein-cysteine farnesyltransferase activity
Proteins in PDR annotated with:
   This term: 16 [Search]
   Term or descendants: 16 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004660 - protein farnesyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle