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Protein Overview: SPBC776.15c

General Information:
Name(s) found: SPBC776.15c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • dihydrolipoamide S-succinyltransferase, e2 component of oxoglutarate dehydrogenase complex [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 452 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial oxoglutarate dehydrogenase complex [ICLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    mitochondrial nucleoid [ISSLink to PubMed article]
    Biological Process: tricarboxylic acid cycle [ISSLink to PubMed article]
    2-oxoglutarate metabolic process [ISSLink to PubMed article]
    Molecular Function: dihydrolipoyllysine-residue succinyltransferase activity [ISSLink to PubMed article]
    lipoic acid binding [IEA]
    oxidoreductase activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSYGNGFRM MAKCLLSLRS GYSVTAPVSK SMANVLWARY ASTRIKTPPF PESITEGTLA  60
   61 QWLKQPGEYV NKDEEIASVE TDKIDAPVTA PDAGVLKEQL VKEGDTITID QDIAVIDTSA 120
  121 APPEGGSAGP KKDEVKTADA DAAKDLSTPQ DSSKPIEEKP MPDLGAEQKE SAPSSTKPAP 180
  181 DAKEPEFSSP KPKPAKSEPV KQSKPKATET ARPSSFSRNE DRVKMNRMRL RIAERLKESQ 240
  241 NRAASLTTFN ECDMSAVVAL RKKYKDEILK ETGVKIGFMS FFSKACTQAM KQIPAINGSI 300
  301 EGEGKGDTLV YRDFCDLSIA VATPKGLVTP VIRNAESMSL LEIESAIATL GSKARAGKLA 360
  361 IEDMASGTFT ISNGGIFGSL YGTPIINLPQ TAVLGLHAIK ERPVVINGQV VPRPMMYLAL 420
  421 TYDHRMVDGR EAVTFLRLVK EYIEDPAKML LV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..214] PSI-BLAST 22.39794 The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
    2 View Details [215..452] PSI-BLAST 87.30103 Dihydrolipoamide succinyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • S-succinyltransferase activity
    		•  10.0778678835755 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  10.0778678835755 bayes_pls_golite062009
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  9.65061123545754 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  9.64995677986911 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  9.49696044977584 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  8.45313874919036 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  8.17557182322815 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  6.86215901871647 bayes_pls_golite062009
  • acyltransferase activity
    		•  6.83977352892719 bayes_pls_golite062009
  • succinyltransferase activity
    		•  6.58826720904067 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  6.40483178382327 bayes_pls_golite062009
  • acetyltransferase activity
    		•  6.08159176722072 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  5.93985773477717 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.60481199262496 bayes_pls_golite062009
  • carnitine O-acyltransferase activity
    		•  2.87366177129153 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.54513901872655 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  1.33852311685118 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  1.22729402619659 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  1.22729402619659 bayes_pls_golite062009
  • transferase activity
    		•  1.08341671157927 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  1.00868366840715 bayes_pls_golite062009
  • binding
    		•  0.801074244553007 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  0.79135670574828 bayes_pls_golite062009
  • O-acetyltransferase activity
    		•  0.54660034926676 bayes_pls_golite062009
  • protein binding
    		•  0.00454070917775817 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle