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Protein Overview: mlo3

General Information:
Name(s) found: mlo3 / SPBC1D7.04 [Sanger Pombe]
Description(s) found:
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  • pir||T39861 mlo3 protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|2498564|sp|Q09330.1|MLO3_SCHPO RecName: Full=mRNA export protein mlo3; AltName: Full=RNA-annealing protein mlo3 [NCBI NR]
  • gi|2326859|emb|CAB10980.1| RNA annealing factor Mlo3 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112507|ref|NP_595715.1| RNA annealing factor Mlo3 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1597736|gb|AAB41270.1| ORF [Schizosaccharomyces pombe] [NCBI NR]
  • RNA annealing factor Mlo3 [Sanger Pombe]
  • mRNA export protein mlo3 OS=Schizosaccharomyces pombe GN=mlo3 PE=1 SV=1 [Swiss-Prot]
  • MLO3 PROTEIN; INTERFERES WITH MITOTIC CHROMOSOME SEGREGATION: Q09330; [pompepVF.fasta]
  • Protein mlo3 [pompep4896]
  • |mlo3||putative TREX complex component [pompepnew.fasta]
  • |mlo3||TREX complex (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • mlo3 protein [Schizosaccharomyces pombe]gi|2326859|emb|CAB10980.1| mlo3 [Schizosaccharomyces pombe]gi|7492200|pir||T39861 mlo3 protein - fission yeast (Schizosaccharomyces pombe)gi|1597736|gb|AAB41270.1| ORF [Schizosaccharomyces pombe]gi|2498564|sp|Q0 [nrdb_11152004_Chlamydomonas]
  • |mlo3||TREX complex |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q09330) Protein mlo3 [pompep4896_normal_reversed]
  • |mlo3||RNA annealing factor Mlo3|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC1D7.04 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC1D7.04 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • ORF [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • |mlo3||RNA binding protein Mlo3|Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • mRNA export protein mlo3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mlo3 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 199 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    transcription export complex [ISSLink to PubMed article]
    Biological Process: poly(A)+ mRNA export from nucleus [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    RNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMELDQSLD AIIASKPKGG IRKRRARSNK PKPTKNAKPA VNTASALKSV ISEESKIIVS  60
   61 NLPTDVTEAQ VKELFVKSIG PCKRVSLAYG PNGRSKGIAT IIFSRPGDAT RAYEQYEGRL 120
  121 VDGTRKMKVE IILDPSRQLN SLAARVSPAS NASATASKNG AKSSKRKTTR RRRTPNRPKK 180
  181 SAEELDKEMD DYFGSNEKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] PSI-BLAST 16.09691 Poly(A)-binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  4.43921816934576 bayes_pls_golite062009
  • binding
    		•  3.19379300171257 bayes_pls_golite062009
  • mRNA binding
    		•  3.1794312979994 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.34356093608328 bayes_pls_golite062009
  • protein binding
    		•  1.52056358240529 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.851308060174055 bayes_pls_golite062009
  • transporter activity
    		•  0.628672636801176 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.505106991526286 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.414871108842203 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.182749906784328 bayes_pls_golite062009
  • poly-purine tract binding
    		•  0.15653271757169 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.11509546367801 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.096231856558874 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.059732432409948 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0510390778764699 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0484248928275733 bayes_pls_golite062009
  • poly(A) RNA binding
    		•  0.0459878286238641 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle