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Protein Overview: mam4

General Information:
Name(s) found: mam4 / SPAC10F6.12c [Sanger Pombe]
Description(s) found:
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  • gi|2661617|emb|CAA15725.1| protein-S isoprenylcysteine O-methyltransferase Mam4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114175|ref|NP_593263.1| protein-S isoprenylcysteine O-methyltransferase Mam4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1906802|dbj|BAA18999.1| farnesyl cysteine carboxyl methyltransferase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|14548108|sp|P87014.1|MAM4_SCHPO RecName: Full=Protein-S-isoprenylcysteine O-methyltransferase; AltName: Full=Isoprenylcysteine carboxylmethyltransferase; AltName: Full=Prenylcysteine carboxyl methyltransferase; Short=pcCMT; AltName: Full=Prenylated pro [NCBI NR]
  • pir||T43237 protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) [similarity] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • protein-S isoprenylcysteine O-methyltransferase Mam4 [Sanger Pombe]
  • Protein-S-isoprenylcysteine O-methyltransferase OS=Schizosaccharomyces pombe GN=mam4 PE=2 SV=1 [Swiss-Prot]
  • PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE (EC 2.1.1.100): P87014; [pompepVF.fasta]
  • Protein-S isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT) [pompep4896]
  • |mam4||protein-s isoprenylcysteine o-methyltransferase [pompepnew.fasta]
  • Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT) [4896.FASTAC]
  • |mam4||protein-s isoprenylcysteine o-methyltransferase (PMID 9032282)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • |mam4||protein-s isoprenylcysteine o-methyltransferase |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • protein-s isoprenylcysteine o-methyltransferase (EC 2.1.1.100) [Schizosaccharomyces pombe]gi|2661617|emb|CAA15725.1| mam4 [Schizosaccharomyces pombe]gi|11282522|pir||T43237 protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) [similarity] - fi [nrdb_11152004_Chlamydomonas]
  • (P87014) Protein-S isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT) [pompep4896_normal_reversed]
  • |mam4||protein-S isoprenylcysteine O-methyltransferase Mam4|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC10F6.12c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • farnesyl cysteine carboxyl methyltransferase [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Protein-S-isoprenylcysteine O-methyltransferase (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT) [nr-271106-contam.fasta]
  • SPAC10F6.12c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Protein-S-isoprenylcysteine O-methyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mam4 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 236 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [ISSLink to PubMed article]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: response to pheromone involved in conjugation with cellular fusion [IC]
    C-terminal protein amino acid methylation [IEA]
    peptide pheromone maturation [IGILink to PubMed article]
    peptide mating pheromone maturation involved in pheromone-induced unidirectional conjugation [IC]
    cellular protein localization [IGILink to PubMed article]
    Molecular Function: protein-S-isoprenylcysteine O-methyltransferase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNLHTSIAV ASICLTSAFL GCVFGLGFFV WIIYGYSIGG FFAFLSLFHL LEFYITARFQ  60
   61 GSQLSWDSFI LNNGKAYWLA MLVGLLECLL SGGKSFAKVI NCLRFPSFLI NFIFSVYQTS 120
  121 ALGFLCLGQY LRSSAMVQAG QSFSHIVASK RNKDHLLVTD GIYAYVRHPS YVGFFIWALG 180
  181 TQMLLGNFVS TLLFSLVLWK FFSQRITTEE AYLVSFFGDS YEQYRKKVPS GIPLIP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] MSA 2.522991 View MSA. No confident structure predictions are available.
    2 View Details [103..236] Pfam 51.508638 No description for PF04140.5 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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