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Protein Overview: glo1

General Information:
Name(s) found: glo1 / SPBC12C2.12c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • glyoxalase I [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 302 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: glutathione metabolic process [IDALink to PubMed article]
    methylglyoxal catabolic process to D-lactate [IMPLink to PubMed article]
    response to osmotic stress [TASLink to PubMed article]
    cellular response to stress [IEPLink to PubMed article]
    Molecular Function: zinc ion binding [IDALink to PubMed article]
    nickel ion binding [IEA]
    manganese ion binding [IEA]
    lactoylglutathione lyase activity [IDALink to PubMed article][IGILink to PubMed article]
    cobalt ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTTDMSTY KLNHTMIRVK DLDKSLKFYT EVFGMKLIDQ WVFEENEFSL SFLAFDGPGA  60
   61 LNHGVERSKR EGILELTYNF GTEKKEGPVY INGNTEPKRG FGHICFTVDN IESACAYLES 120
  121 KGVSFKKKLS DGKMKHIAFA LDPDNYWIEL VSQSETKPKA NISNFRFNHT MVRVKDPEPS 180
  181 IAFYEKLGMK VIDKADHPNG KFTNYFLAYP SDLPRHDREG LLELTHNWGT EKESGPVYHN 240
  241 GNDGDEKGYG HVCISVDNIN AACSKFEAEG LPFKKKLTDG RMKDIAFLLD PDNYWVEVIE 300
  301 QK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 26.0 Glyoxalase I (lactoylglutathione lyase)
    2 View Details [160..302] PSI-BLAST 5.045757 No description for 2qqzA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lactoylglutathione lyase activity
    		•  3.91334658149719 bayes_pls_golite062009
  • binding
    		•  1.68530537296561 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  1.44168339433372 bayes_pls_golite062009
  • catalytic activity
    		•  1.21778090213032 bayes_pls_golite062009
  • protein binding
    		•  0.28912087714501 bayes_pls_golite062009
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
    		•  0.0991913830827656 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle