YRC Public Data Repository - Protein Structure Prediction

Protein:	glo1
Organism:	Schizosaccharomyces pombe
Length:	302 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for glo1.

Description	E-value	Query Range	Subject Range
gi\|85097393 - gi\|85097393\|ref\|XP_960441.1\| lactoylglutathione lyase [Neurospora crassa OR74A] gi\|28921932, gi\|... - gi\|32407160\|ref\|XP_324172.1\| hypothetical protein [Neurospora crassa], gi\|28921932\|gb\|EAA31205.1\| la...	210.0	[0..1]	[302..1]
gi\|67527845, gi\|... - gi\|67527845\|ref\|XP_661778.1\| hypothetical protein AN4174.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	209.0	[0..3]	[302..1]
gi\|116202059, gi... - gi\|88177432\|gb\|EAQ84900.1\| hypothetical protein CHGG_08914 [Chaetomium globosum CBS 148.51], gi\|1162...	207.0	[0..1]	[302..1]
gi\|90306260, gi\|... - gi\|90306260\|gb\|EAS35891.1\| lactoylglutathione lyase [Coccidioides immitis RS], gi\|119193739\|ref\|XP_0...	206.0	[0..3]	[302..1]
gi\|159124248 - gi\|159124248\|gb\|EDP49366.1\| lactoylglutathione lyase [Aspergillus fumigatus A1163] gi\|70991673, gi\|... - gi\|70991673\|ref\|XP_750685.1\| lactoylglutathione lyase [Aspergillus fumigatus Af293], gi\|66848318\|gb\|...	205.0	[0..1]	[302..1]
gi\|42553364, gi\|... - gi\|46135933\|ref\|XP_389658.1\| hypothetical protein FG09482.1 [Gibberella zeae PH-1], gi\|42553364\|gb\|E...	203.0	[0..1]	[302..1]
gi\|30016920 - gi\|30016920\|gb\|AAP03992.1\| glyoxalase I [Paracoccidioides brasiliensis]	203.0	[0..3]	[302..1]
gi\|83767226 - gi\|83767226\|dbj\|BAE57365.1\| unnamed protein product [Aspergillus oryzae] gi\|169769795 - gi\|169769795\|ref\|XP_001819367.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|238487876, gi... - gi\|238487876\|ref\|XP_002375176.1\| lactoylglutathione lyase [Aspergillus flavus NRRL3357], gi\|22070005...	201.0	[0..3]	[302..1]
gi\|83267732 - gi\|83267732\|gb\|ABB89044.1\| glyoxalase I [Verticillium dahliae]	197.0	[0..1]	[302..34]
gi\|160703925, gi... - gi\|169619922\|ref\|XP_001803373.1\| glyoxylase I [Phaeosphaeria nodorum SN15], gi\|160703925\|gb\|EAT79488... gi\|50295647 - gi\|50295647\|gb\|AAT73077.1\| glyoxylase I [Phaeosphaeria nodorum]	193.0	[0..3]	[302..1]

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Predicted Domain #1

Region A:
Residues: [1-159]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTTDMSTY KLNHTMIRVK DLDKSLKFYT EVFGMKLIDQ WVFEENEFSL SFLAFDGPGA  60
   61 LNHGVERSKR EGILELTYNF GTEKKEGPVY INGNTEPKRG FGHICFTVDN IESACAYLES 120
  121 KGVSFKKKLS DGKMKHIAFA LDPDNYWIEL VSQSETKPK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.0
Match:	1froA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.91334658149719	bayes_pls_golite062009
binding	1.68530537296561	bayes_pls_golite062009
carbon-sulfur lyase activity	1.44168339433372	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
protein binding	0.28912087714501	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	0.0991913830827656	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [160-302]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANISNFRFNH TMVRVKDPEP SIAFYEKLGM KVIDKADHPN GKFTNYFLAY PSDLPRHDRE  60
   61 GLLELTHNWG TEKESGPVYH NGNDGDEKGY GHVCISVDNI NAACSKFEAE GLPFKKKLTD 120
  121 GRMKDIAFLL DPDNYWVEVI EQK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.045757
Match:	2qqzA
Description:	No description for 2qqzA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: