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Protein Overview: tif32

General Information:
Name(s) found: tif32 / SPBC17D11.05 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • translation initiation factor eIF3a [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 932 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic 43S preinitiation complex [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    eukaryotic translation initiation factor 3 complex [ISSLink to PubMed article]
    Biological Process: positive regulation of translational initiation [ICLink to PubMed article]
    regulation of translation in response to nitrogen starvation [IPILink to PubMed article]
    translational initiation [ISSLink to PubMed article]
    Molecular Function: translation initiation factor activity [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]
    arylformamidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPQGKPEN VLRLADELIA LDQHSSALQS LHETIVLKRS RNAQGFSLEP IMMRFIELCV  60
   61 HLRKGKIAKE GLYTYKNAVQ NTSVTAIENV VKHFIELANK RVQEAQEKAD KISVEYVDDL 120
  121 EATETPESIM MSLVSGDLSK SRTDRALVTP WLKFLWDAYR TVLDILRNNA RLEVMYQLIA 180
  181 NSAFQFCLKY QRKTEFRRLC ELLRSHLGNA SKFSNAPHSI NLNDAETMQR HLDMRFSQLN 240
  241 VAVELELWQE AFRSIEDIHS LLTFSKRAPA AVMLGNYYRK LIKIFLVCDN YLLHAAAWNR 300
  301 YFTFTNVQKP ATANFVILSA LSIPIIDANK LSGPSIEAED AKSKNARLAL LLNLSKTPTR 360
  361 ETLIKDAISR GVLSFCDQAI RDLYQILEVE FHPLSICKKL QPIIKRLAES NDTAQYIRPL 420
  421 QQVILTRLFQ QLSQVYDSIS LKYVMDLATF EEPYDFNPGQ IEKFIMNGNK KGAFSIRLNH 480
  481 IENSISFSSD LFSNPIKSSD SVSLQSTPSE LITSQLTRIA KSLSSVLMRF DTDFCLLRKQ 540
  541 QAEAAYERAQ AGVEQERKAV IAQRSLLELR RGQADTLATQ REAELAAQRA LKQKQESEAE 600
  601 SLRVQEEINK RNAERIRREK EAIRINEAKK LAEELKAKGG LEVNAEDLEH LDADKLRAMQ 660
  661 IEQVEKQNKS MNERLRVIGK RIDHLERAYR REAIPLWEED AKQQAEHDRE IFYEREKQRK 720
  721 EVQERKHEQA IKDKKAFAQF ASYIHAYKQN IDDERDKAYQ EAYAKAKNVI DAERERQRKE 780
  781 IFEQKLAEAI REAEEEAARA AEEEANRELH EQEEAQKRAI EERTRAAREA KEREQREMAE 840
  841 KLERQRRIQQ ERDEEISRKL AEKAAARRAN IGASSPSPGA WRRGGASAGG VSRDSPRYSR 900
  901 GGYSRGSVPP RETLAPSKGA YVPPSRRNQQ QQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] deduced N/A No confident structure predictions are available.
    2 View Details [202..324] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [325..413] deduced N/A No confident structure predictions are available.
    4 View Details [414..538] FFAS03 2.1 Solution structure of the PCI domain
    5 View Details [539..932] PSI-BLAST 14.69897 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  3.79393646713264 bayes_pls_golite062009
  • DNA binding
    		•  3.49224482622525 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.44526829828119 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.974370828939 bayes_pls_golite062009
  • transcription factor activity
    		•  2.7749459098618 bayes_pls_golite062009
  • binding
    		•  2.73671056234733 bayes_pls_golite062009
  • structural molecule activity
    		•  2.72616711594099 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.22614366856306 bayes_pls_golite062009
  • transcription activator activity
    		•  1.09150217878747 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.00086155936348 bayes_pls_golite062009
  • protein binding
    		•  0.726445167461826 bayes_pls_golite062009
  • RNA binding
    		•  0.352569950847387 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.294869091673654 bayes_pls_golite062009
  • mRNA binding
    		•  0.262190946714123 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle