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Protein Overview: uga1

General Information:
Name(s) found: uga1 / SPAC19D5.07 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • 4-aminobutyrate aminotransferase (GABA transaminase) [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 474 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: glutamate metabolic process [IDALink to PubMed article]
    gamma-aminobutyric acid catabolic process [IDALink to PubMed article]
    nitrogen utilization [ISSLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IDALink to PubMed article]
    4-aminobutyrate transaminase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTATVTES THFFPNEPQG PSIKTETIPG PKGKAAAEEM SKYHDISAVK FPVDYEKSIG  60
   61 NYLVDLDGNV LLDVYSQIAT IPIGYNNPTL LKAAKSDEVA TILMNRPALG NYPPKEWARV 120
  121 AYEGAIKYAP KGQKYVYFQM SGSDANEIAY KLAMLHHFNN KPRPTGDYTA EENESCLNNA 180
  181 APGSPEVAVL SFRHSFHGRL FGSLSTTRSK PVHKLGMPAF PWPQADFPAL KYPLEEHVEE 240
  241 NAKEEQRCID QVEQILTNHH CPVVACIIEP IQSEGGDNHA SPDFFHKLQA TLKKHDVKFI 300
  301 VDEVQTGVGS TGTLWAHEQW NLPYPPDMVT FSKKFQAAGI FYHDLALRPH AYQHFNTWMG 360
  361 DPFRAVQSRY ILQEIQDKDL LNNVKSVGDF LYAGLEELAR KHPGKINNLR GKGKGTFIAW 420
  421 DCESPAARDK FCADMRINGV NIGGCGVAAI RLRPMLVFQK HHAQILLKKI DELI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..474] PSI-BLAST 102.0 4-AMINOBUTYRATE-AMINOTRANSFERASE FROM PIG

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-aminobutyrate transaminase activity
    		•  9.08769857759091 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase binding
    		•  8.44659094913875 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  3.359406422625 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • N-succinyltransferase activity
    		•  1.52003194822848 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.46601963907552 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.46601963907552 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
    		•  1.4383564662931 bayes_pls_golite062009
  • glutamate decarboxylase activity
    		•  1.34215658716536 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.19150094103499 bayes_pls_golite062009
  • binding
    		•  0.892049641082766 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.523223426448441 bayes_pls_golite062009
  • ornithine-oxo-acid transaminase activity
    		•  0.311107335626334 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.2609065149092 bayes_pls_golite062009
  • kynureninase activity
    		•  0.187611110950763 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.186646089509162 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • hydrolase activity
    		•  0.158765164178244 bayes_pls_golite062009
  • amine binding
    		•  0.14702601411039 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.0833010353195099 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0380916685195369 bayes_pls_golite062009
  • DNA binding
    		•  0.0281750086102144 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle