YRC Public Data Repository - Protein Structure Prediction

Protein:	uga1
Organism:	Schizosaccharomyces pombe
Length:	474 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for uga1.

Description	E-value	Query Range	Subject Range
gi\|119524573, gi... - gi\|119719453\|ref\|YP_919948.1\| 4-aminobutyrate aminotransferase [Thermofilum pendens Hrk 5], gi\|11952...	412.0	[0..19]	[474..2]
ARGD_THETN - Acetylornithine aminotransferase OS=Thermoanaerobacter tengcongensis GN=argD PE=3 SV=1 ARGD_CALS4 - Acetylornithine aminotransferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 1...	405.0	[0..40]	[474..5]
gi\|167039319, gi... - gi\|167039319\|ref\|YP_001662304.1\| acetylornithine and succinylornithine aminotransferase [Thermoanaer... gi\|242256153, gi... - gi\|242256153\|ref\|ZP_04801049.1\| acetylornithine and succinylornithine aminotransferase [Thermoanaero...	397.0	[0..39]	[474..5]
gi\|241883989, gi... - gi\|241903682\|ref\|ZP_04788402.1\| acetylornithine and succinylornithine aminotransferase [Thermoanaero... gi\|76588469, gi\|... - gi\|76796199\|ref\|ZP_00778566.1\| Acetylornithine and succinylornithine aminotransferase [Thermoanaerob...	395.0	[0..39]	[473..5]
gi\|113942343, gi... - gi\|159896672\|ref\|YP_001542919.1\| aminotransferase class-III [Herpetosiphon aurantiacus ATCC 23779], ...	394.0	[0..26]	[474..17]
gi\|116621553, gi... - gi\|67932454\|ref\|ZP_00525597.1\| Aminotransferase class-III [Solibacter usitatus Ellin6076], gi\|678603...	391.0	[0..25]	[474..16]
gi\|74219159 - gi\|74219159\|dbj\|BAE26718.1\| unnamed protein product [Mus musculus]	390.0	[0..1]	[474..5]
gi\|46434853, gi\|... - gi\|68485478\|ref\|XP_713322.1\| hypothetical protein CaO19.5641 [Candida albicans SC5314], gi\|68485383\|... orf19.5641, orf1... - CAR2 CGDID:CAL0000636 Assembly 19, Contig19-10231 (13951, 12641) CDS, reverse complemented, translat...	388.0	[0..32]	[474..10]
ARGD_SYNY3 - Acetylornithine aminotransferase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=argD PE=3 SV=1 gi\|7434142 - pir\|\|S75245 N-acetylornithine aminotransferase - Synechocystis sp. (strain PCC 6803) ARGD_SYNY3 - Acetylornithine aminotransferase OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=argD P...	388.0	[0..17]	[474..11]

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Predicted Domain #1

Region A:
Residues: [1-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTATVTES THFFPNEPQG PSIKTETIPG PKGKAAAEEM SKYHDISAVK FPVDYEKSIG  60
   61 NYLVDLDGNV LLDVYSQIAT IPIGYNNPTL LKAAKSDEVA TILMNRPALG NYPPKEWARV 120
  121 AYEGAIKYAP KGQKYVYFQM SGSDANEIAY KLAMLHHFNN KPRPTGDYTA EENESCLNNA 180
  181 APGSPEVAVL SFRHSFHGRL FGSLSTTRSK PVHKLGMPAF PWPQADFPAL KYPLEEHVEE 240
  241 NAKEEQRCID QVEQILTNHH CPVVACIIEP IQSEGGDNHA SPDFFHKLQA TLKKHDVKFI 300
  301 VDEVQTGVGS TGTLWAHEQW NLPYPPDMVT FSKKFQAAGI FYHDLALRPH AYQHFNTWMG 360
  361 DPFRAVQSRY ILQEIQDKDL LNNVKSVGDF LYAGLEELAR KHPGKINNLR GKGKGTFIAW 420
  421 DCESPAARDK FCADMRINGV NIGGCGVAAI RLRPMLVFQK HHAQILLKKI DELI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	102.0
Match:	1ohvA
Description:	4-AMINOBUTYRATE-AMINOTRANSFERASE FROM PIG
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-aminobutyrate transaminase activity	9.08769857759091	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase binding	8.44659094913875	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	3.359406422625	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
N-succinyltransferase activity	1.52003194822848	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.46601963907552	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.46601963907552	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	1.4383564662931	bayes_pls_golite062009
glutamate decarboxylase activity	1.34215658716536	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.19150094103499	bayes_pls_golite062009
binding	0.892049641082766	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.523223426448441	bayes_pls_golite062009
ornithine-oxo-acid transaminase activity	0.311107335626334	bayes_pls_golite062009
N-acyltransferase activity	0.2609065149092	bayes_pls_golite062009
kynureninase activity	0.187611110950763	bayes_pls_golite062009
nucleic acid binding	0.186646089509162	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
hydrolase activity	0.158765164178244	bayes_pls_golite062009
amine binding	0.14702601411039	bayes_pls_golite062009
cystathionine beta-lyase activity	0.0833010353195099	bayes_pls_golite062009
transcription regulator activity	0.0380916685195369	bayes_pls_golite062009
DNA binding	0.0281750086102144	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: