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Protein Overview: tif223

General Information:
Name(s) found: tif223 / SPAC4D7.09 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • translation initiation factor eIF2B [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    eukaryotic translation initiation factor 2B complex [ISSLink to PubMed article]
    ribosome [ISSLink to PubMed article]
    Biological Process: positive regulation of translational initiation [ICLink to PubMed article]
    translational initiation [ISSLink to PubMed article]
    Molecular Function: translation initiation factor activity [ISSLink to PubMed article]
    nucleotidyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLYEHAALP LASSPSILGP ISGGRNRGNI QLQSIPIEFQ AVVFAGFGNS LYPLTGSDAL  60
   61 PKALLPIGNK PMLHYPLYWL EAAGFTSAIL ICMEEAEAHI NAWLRSGYEG HMRIHVEAPT 120
  121 ILDDSKSSAD ALRAVSHLIK SQKMLTDTHQ NDFVCLSCDS IVGLPPIYGL DKFRLDNPSA 180
  181 LAVYSPVLKY EHITSQSKEI DAKQLIGIEE KTSRLLYAKS SADVGSDFTF RMSLLWKHPR 240
  241 VTLNTNLSDA HIFVFKHWVI DLIREKESIS SIRGDLIPYL VKCQYQKSFT VRENIQRFLS 300
  301 SPNNIDNYDG GLSSQEIKIN ALIAKDGIIC SRANNLPNYF ELNKCIAKLT PEQRLVDVTV 360
  361 SERALVGADC MVNEGTTIKD NSNIKKSIIG KNCVIGKGVV VSNSILMDNI VVEDGVRLES 420
  421 CIVASGAQIG AKSKLRECEI GVDHRVEAGR IARGERLVDM EKIETDMD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..468] PSI-BLAST 49.0 N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity
    		•  2.17535315350752 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.86990263440735 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.49149681135671 bayes_pls_golite062009
  • glucose binding
    		•  1.05456452815784 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.796949457473955 bayes_pls_golite062009
  • acyltransferase activity
    		•  0.741838450922005 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  0.717805296858439 bayes_pls_golite062009
  • binding
    		•  0.667238976803188 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  0.619458068514795 bayes_pls_golite062009
  • sugar binding
    		•  0.598232027709749 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.555398952276587 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  0.319932817519902 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle