YRC Public Data Repository - Protein Structure Prediction

Protein:	tif223
Organism:	Schizosaccharomyces pombe
Length:	468 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tif223.

Description	E-value	Query Range	Subject Range
gi\|18893895, gi\|... - gi\|18978100\|ref\|NP_579457.1\| NDP-sugar synthase [Pyrococcus furiosus DSM 3638], gi\|18893895\|gb\|AAL81...	198.0	[0..40]	[452..3]
GLMU_HAES1 - Bifunctional protein GlmU OS=Haemophilus somnus (strain 129Pt) GN=glmU PE=3 SV=1	197.0	[0..35]	[467..1]
gi\|196253087, gi... - gi\|196253087\|ref\|ZP_03151729.1\| Nucleotidyl transferase [Clostridium thermocellum DSM 4150], gi\|1961... gi\|67851212, gi\|... - gi\|67874439\|ref\|ZP_00504225.1\| transferase hexapeptide repeat:Nucleotidyl transferase:Phosphoglucomu...	197.0	[0..40]	[468..3]
gi\|77977938 - gi\|77977938\|ref\|ZP_00833375.1\| COG1207: N-acetylglucosamine-1-phosphate uridyltransferase (contains ...	197.0	[0..41]	[467..4]
GLMU_ACTSZ - Bifunctional protein GlmU OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) GN=glmU PE=3 SV=...	196.0	[0..35]	[467..1]
GLMU_SALTI - Bifunctional protein glmU OS=Salmonella typhi GN=glmU PE=3 SV=1 GLMU_SALTI - Bifunctional protein GlmU OS=Salmonella typhi GN=glmU PE=3 SV=1 gi\|213646875 - gi\|213646875\|ref\|ZP_03376928.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|29139588, gi\|... - gi\|29143952\|ref\|NP_807294.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|213427473 - gi\|213427473\|ref\|ZP_03360223.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|213052672 - gi\|213052672\|ref\|ZP_03345550.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|16762464 - gi\|16762464\|ref\|NP_458081.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|214001321 - gi\|214001321\|ref\|ZP_03412056.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|213852798 - gi\|213852798\|ref\|ZP_03382330.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco...	196.0	[0..41]	[467..9]
GLMU_SALCH - Bifunctional protein glmU OS=Salmonella choleraesuis GN=glmU PE=3 SV=1 GLMU_SALCH - Bifunctional protein GlmU OS=Salmonella choleraesuis (strain SC-B67) GN=glmU PE=3 SV=1 GLMU_SALCH - Bifunctional protein GlmU OS=Salmonella choleraesuis GN=glmU PE=3 SV=1	196.0	[0..41]	[467..9]
GLMU_SALTY - Bifunctional protein GlmU OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=glmU PE... GLMU_SALTY - Bifunctional protein glmU OS=Salmonella typhimurium GN=glmU PE=3 SV=1 gi\|195632226, gi... - gi\|195632226\|gb\|EDX50710.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_SALHS - Bifunctional protein GlmU OS=Salmonella heidelberg (strain SL476) GN=glmU PE=3 SV=1 gi\|167995196, gi... - gi\|205327084\|gb\|EDZ13848.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... gi\|205336006, gi... - gi\|205336006\|gb\|EDZ22770.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_SALTY - Bifunctional protein GlmU OS=Salmonella typhimurium GN=glmU PE=3 SV=1 lcl\|NC_016856.1_... - [gene=glmU] [protein=bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-ph...	196.0	[0..41]	[467..9]
GLMU_HISS2 - Bifunctional protein GlmU OS=Histophilus somni (strain 2336) GN=glmU PE=3 SV=2	196.0	[0..35]	[467..1]
gi\|7448165, gi\|5... - pir\|\|G75164 mannose-1-phosphate guanyltransferase PAB0317 - Pyrococcus abyssi (strain Orsay), gi\|545... gi\|14520692, gi\|... - gi\|5457908\|emb\|CAB49398.1\| Nucleotidyltransferase [Pyrococcus abyssi GE5], gi\|14520692\|ref\|NP_126167...	195.0	[0..40]	[452..3]

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Predicted Domain #1

Region A:
Residues: [1-468]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLYEHAALP LASSPSILGP ISGGRNRGNI QLQSIPIEFQ AVVFAGFGNS LYPLTGSDAL  60
   61 PKALLPIGNK PMLHYPLYWL EAAGFTSAIL ICMEEAEAHI NAWLRSGYEG HMRIHVEAPT 120
  121 ILDDSKSSAD ALRAVSHLIK SQKMLTDTHQ NDFVCLSCDS IVGLPPIYGL DKFRLDNPSA 180
  181 LAVYSPVLKY EHITSQSKEI DAKQLIGIEE KTSRLLYAKS SADVGSDFTF RMSLLWKHPR 240
  241 VTLNTNLSDA HIFVFKHWVI DLIREKESIS SIRGDLIPYL VKCQYQKSFT VRENIQRFLS 300
  301 SPNNIDNYDG GLSSQEIKIN ALIAKDGIIC SRANNLPNYF ELNKCIAKLT PEQRLVDVTV 360
  361 SERALVGADC MVNEGTTIKD NSNIKKSIIG KNCVIGKGVV VSNSILMDNI VVEDGVRLES 420
  421 CIVASGAQIG AKSKLRECEI GVDHRVEAGR IARGERLVDM EKIETDMD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.0
Match:	1hv9A
Description:	N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	2.17535315350752	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
nucleotidyltransferase activity	1.86990263440735	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.49149681135671	bayes_pls_golite062009
glucose binding	1.05456452815784	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	0.796949457473955	bayes_pls_golite062009
acyltransferase activity	0.741838450922005	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	0.717805296858439	bayes_pls_golite062009
binding	0.667238976803188	bayes_pls_golite062009
UDP-glycosyltransferase activity	0.619458068514795	bayes_pls_golite062009
sugar binding	0.598232027709749	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.555398952276587	bayes_pls_golite062009
O-acyltransferase activity	0.319932817519902	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: