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Protein Overview: pol5

General Information:
Name(s) found: pol5 / SPBC14C8.14c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • DNA polymerase phi [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 959 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: transcription of nuclear rRNA large RNA polymerase I transcript [ICLink to PubMed article]
    rRNA transcription [IMPLink to PubMed article]
    Molecular Function: DNA-directed DNA polymerase activity [IEA]
    protein binding [IPILink to PubMed article]
    rDNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKTQLELF TKLTSNDKAI RLSSAAQLID SLSNEEELKY SLNRLTKGLS SGRESARIGF  60
   61 AVALTELLTR TKDIRATHVL DLLVKHNTAS GNLKGQDERD FYFGLLFGLQ SIVYSGILTH 120
  121 KESTIEDFQR VVDLLLQLSG KKNWLQDVCF YVIYKLVEQI PEISFSSNAF LAVNKLLQTP 180
  181 AVSKSTEGVG LFLCLTRVPD NVKSEEVAMA NWEPAHPLHK SNLVTLSKIM RQADASETGG 240
  241 QNSAWKQKIP MVWKYIFEEY QRKTYSGLAP FHDFWAVVVD EGIFSSTSSL ERKFWGFQIM 300
  301 ELALDYVSSD NIGDIFSKNF LHCLINHLSD EDRYLYRAAK RVTSKLEKVS KQNPTLVYPI 360
  361 AIHLLGERGS LNFDRVTNTK LVEHILPLAD EQGILQLFQL LLSYVKRCPE DIASDTKAVE 420
  421 WRRQWATDTM LSILRSKRSI KQEPWVRELL EIFIAYGYFE VPESEEVIPK FSEGTQNMFR 480
  481 LRLMSALSYL SSSAFQQSQT DHQLGDKNWP YVALNYLLEL EKSPKNNLLI SMDESVIEIV 540
  541 QKSLSVLHKV TKKIDKKAQH LQQLNAFQLL YSLVLLQVYA GDTDSIDVLE DIDNCYSKVF 600
  601 NKKSKRESTS NEPTAMEILT EVMLSLLSRP SLLLRKLVDM LFTSFSEDMN RESIHLICDV 660
  661 LKAKESVKDS EGMFAGEEVE EDAFGETEMD EDDFEEIDTD EIEEQSDWEM ISNQDASDNE 720
  721 ELERKLDKVL EDADAKVKDE ESSEEELMND EQMLALDEKL AEVFRERKKA SNKEKKKNAQ 780
  781 ETKQQIVQFK VKVIDLIDNY YKTQPNNGLG FEFLIPLLEM ILKTKHKVLE EKGQAVFRNR 840
  841 LSKLKWTEEK PSSKNVLEAL KKVHVLCGKK ASLGSTGSSI SQLLLKLLAD TPYLKEGVEV 900
  901 YLKSFLLWIQ EPSKSHYNAN IFHDFINWGA QQRLKHQQTS TAASSPQKTG HHENEKTNH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..660] FFAS03 1.52 Adaptin beta subunit N-terminal fragment
    2 View Details [661..794] MSA 23.060997 View MSA. No confident structure predictions are available.
    3 View Details [795..959] MSA 1.03599 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.4840129457355 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.27889073911459 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.19067997822967 bayes_pls_golite062009
  • actin binding
    		•  1.7228099998642 bayes_pls_golite062009
  • DNA binding
    		•  1.71679738414596 bayes_pls_golite062009
  • protein binding
    		•  1.41127231900194 bayes_pls_golite062009
  • transcription factor activity
    		•  1.01026749293758 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.301301625996911 bayes_pls_golite062009
  • structural molecule activity
    		•  0.279533827088985 bayes_pls_golite062009
  • RNA binding
    		•  0.243875756041061 bayes_pls_golite062009
  • transcription activator activity
    		•  0.142253868848261 bayes_pls_golite062009
  • transcription factor binding
    		•  8.79739237675814E-4 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle