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Protein Overview: spb70

General Information:
Name(s) found: spb70 / SPCC553.09c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • DNA polymerase alpha B-subunit [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    alpha DNA polymerase:primase complex [TASLink to PubMed article]
    nuclear chromatin [ICLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: DNA replication initiation [NASLink to PubMed article]
    DNA replication, synthesis of RNA primer [ICLink to PubMed article]
    Molecular Function: DNA binding [IEA]
    DNA-directed DNA polymerase activity [IEA]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFPIDDEEL LDERNKLLQI CNMDEQTMFY KWESWCLQRG NTPKLDLDTF KAFAKDMKFQ  60
   61 MERQVKATLK QNPERKSIKQ IPGMNIDSIL GLPVKTTASG DSLMQESKPS TETFELNSSD 120
  121 AGRVLEVLNK ELKIVTSKPS APSKLVIVAN FDLKAFNYRI MYQKLYDSSE VLDDRIELFS 180
  181 ALTCRKYNIS DEDLANPSEL TQEPVVVVGR IVVESTNLGG RLNQNSILLE SSRRLGAGVR 240
  241 VRLKVDDLPS YSIFPGQIVS VKGSNPSGNM FIAKEILPIP PLPFPSSSKQ EHATFVANTN 300
  301 NQPISIYIAS GPWSLRDDLS FSPLKSMISY VNKNPVDLVI LCGPFLDINH ILIRTGNITG 360
  361 TSATSLEELF KERVTPILSQ LTCPCILIPH INDAASDHPA WPQDAFNRVA LGLPSNFKCF 420
  421 PNPCMFSIND VVFGVSTNDI LLHTSREELF RLPSHGNLFA RLVSHVLHQR HFYPLFPGGS 480
  481 LEKCNPSNLD IAHLKLGEFL NTMPDILILP SDLRYFVKNV ENVVSLNPGK ATKGINLGTF 540
  541 AKLTIAPLEL GDNGSSNHYS HRVWLRTKAE ILKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] Pfam 93.823909 No description for PF08418.1 was found. No confident structure predictions are available.
    2 View Details [218..284] deduced N/A No confident structure predictions are available.
    3 View Details [285..574] FFAS03 1.52 Structural and biochemical characterization of Yfce, a phosphoesterase from E. coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.06438091629012 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.87325132707337 bayes_pls_golite062009
  • catalytic activity
    		•  1.30037658165549 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.17916462117542 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.950264524479969 bayes_pls_golite062009
  • phosphatase activity
    		•  0.829761417192212 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.768201004870964 bayes_pls_golite062009
  • structural molecule activity
    		•  0.211411396269789 bayes_pls_golite062009
  • hydrolase activity
    		•  0.070797330694107 bayes_pls_golite062009
  • protein binding
    		•  0.0115800495687428 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle