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Protein Overview: cwg2

General Information:
Name(s) found: cwg2 / SPAC2E1P5.04c [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • geranylgeranyltransferase I beta subunit Cwg2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 355 amino acids

    Gene Ontology:
    Cellular Component: CAAX-protein geranylgeranyltransferase complex [NASLink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: 1,3-beta-glucan biosynthetic process [IMPLink to PubMed article]
    establishment or maintenance of cell polarity [IMPLink to PubMed article]
    protein amino acid geranylgeranylation [ICLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPILink to PubMed article]
    protein geranylgeranyltransferase activity [IDALink to PubMed article]
    Rab geranylgeranyltransferase activity [IGILink to PubMed article]
    CAAX-protein geranylgeranyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELTRAKHIA FFKRHLILFP TPYEEHDCER TVLAFFCLLG LDLLNALNTI DDDDKKSWIE  60
   61 WIYKNYVTKE SKGIKYSGFQ AYRTGIQPIS FEQEPQLAGT VFSICCLLFL GDNLSRIDRD 120
  121 LIKNFVELCK TSQGHFRSIA VPSCSDQDMR QLYMATTIAS LLDFSLSDPL CSIQYIKSCQ 180
  181 RYEGGFSLLP YGEAHAGATF CALASWSLIL KMIPNSSLNT SNQSYNLMDC VPKVERLIRW 240
  241 LASRQLSSGG LNGRTNKDVD TCYAYWVLSS LKLLDALPFI DGGELEKYLL LHAQHALGGF 300
  301 SKTPGEFPDV LHSALGLYAM AYQDDKSFPK VNADIHMTSK YINICRDCIQ AAKGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..355] PSI-BLAST 95.39794 Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein geranylgeranyltransferase activity
    		•  12.5056881810294 bayes_pls_golite062009
  • prenyltransferase activity
    		•  11.2095419035102 bayes_pls_golite062009
  • CAAX-protein geranylgeranyltransferase activity
    		•  10.5569796788906 bayes_pls_golite062009
  • protein prenyltransferase activity
    		•  8.21177558804895 bayes_pls_golite062009
  • Rab geranylgeranyltransferase activity
    		•  6.2955313775009 bayes_pls_golite062009
  • protein farnesyltransferase activity
    		•  4.15546866363415 bayes_pls_golite062009
  • binding
    		•  1.68564752993879 bayes_pls_golite062009
  • protein binding
    		•  1.45455287827127 bayes_pls_golite062009
  • transferase activity
    		•  1.0950430724883 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.854896924803117 bayes_pls_golite062009
  • catalytic activity
    		•  0.497699107100544 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.75

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle