Protein Overview: csx1

General Information:
Name(s) found:	csx1 / SPAC17A2.09c [Sanger Pombe]
Description(s) found: Found 16 descriptions. SHOW ALL	RNA-binding protein Csx1 [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	632 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] cytosol [IDA]
Biological Process:	regulation of mRNA stability involved in response to stress [IMP]
Molecular Function:	RNA binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIDCLYRRS SLFDTSFVPL HSSIPATSKM SASNSDVNAP ISPVVDEGKS ELVSPTLERL  60
   61 VAPFNCSPSS TPLQDVAGVG SKMSDTLWMG DLEPWMDATF IQQLWASLNE PVNVKVMRSK 120
  121 ASSSETLISY CFVQFSSSAA AERALMKYNN TMIPGAHCTF KLNWATGGGI QHNNFVSRDP 180
  181 EFSIFVGDLL PTTEDSDLFM TFRSIYPSCT SAKIIVDPVT GLSRKYGFVR FSSEKEQQHA 240
  241 LMHMQGYLCQ GRPLRISVAS PKSRASIAAD SALGIVPTST SNRQPNQDLC SMDPLNTTVF 300
  301 VGGLASNLSE KDLQVCFQPF GRILNIKIPF GKGCGFVQYS EKSAAEKAIN TMQGALVGTS 360
  361 HIRLAWGHNT LPVSALSQSQ SQVSDEGFDR TLSANQIFGM NQSVIGANSG SSNSSGSSLK 420
  421 SAPVSPRTAA AQSLLPNSVV SSINGMNSVN FSTISPPPLS RSASISPTLS GSGSGLTPLS 480
  481 SHFPSAATGL VGGQVYPQSS VLQSSKINGS AKVQPSVKLP EWLQPFSGNN HNSFATQDLL 540
  541 TRVSSLKLVD DEQPASLNGS AFQARASRPW NLGRERQSSL IDLRHELEQN ENGLEKSGFG 600
  601 LNLRGRLPPR SYSTFNCTGQ YLQPSLRLSR DS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..279]	PSI-BLAST	49.221849	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
2	View Details	[280..371]	PSI-BLAST	17.0	Polypyrimidine tract-binding protein
3	View Details	[372..488]	deduced	N/A	No confident structure predictions are available.
4	View Details	[489..632]	PSI-BLAST	21.0	poly(A) binding protein

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
RNA binding	4.63987691433124	bayes_pls_golite062009
nucleic acid binding	4.05055109233024	bayes_pls_golite062009
mRNA binding	3.54495985180603	bayes_pls_golite062009
binding	3.00411894202318	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
	1.35163561991147	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription regulator activity	0.884269546056316	bayes_pls_golite062009
DNA binding	0.841333741555926	bayes_pls_golite062009
mRNA 3'-UTR binding	0.599389001184667	bayes_pls_golite062009
poly-pyrimidine tract binding	0.544292786424842	bayes_pls_golite062009
transcription factor activity	0.182209144070426	bayes_pls_golite062009

2

Term	Confidence	Notes
RNA binding	4.63987691433124	bayes_pls_golite062009
nucleic acid binding	4.05055109233024	bayes_pls_golite062009
mRNA binding	3.54495985180603	bayes_pls_golite062009
binding	3.00411894202318	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
	1.35163561991147	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription regulator activity	0.884269546056316	bayes_pls_golite062009
DNA binding	0.841333741555926	bayes_pls_golite062009
mRNA 3'-UTR binding	0.599389001184667	bayes_pls_golite062009
poly-pyrimidine tract binding	0.544292786424842	bayes_pls_golite062009
transcription factor activity	0.182209144070426	bayes_pls_golite062009

3

No functions predicted.

4

Term	Confidence	Notes
RNA binding	3.6067898155184	bayes_pls_golite062009
mRNA binding	3.56033450577296	bayes_pls_golite062009
single-stranded RNA binding	3.03728178586535	bayes_pls_golite062009
eukaryotic initiation factor 4G binding	2.95613613030851	bayes_pls_golite062009
nucleic acid binding	2.91838330515065	bayes_pls_golite062009
poly(A) RNA binding	2.66269581586161	bayes_pls_golite062009
poly-purine tract binding	2.60937924017999	bayes_pls_golite062009
binding	2.12178506555766	bayes_pls_golite062009
protein binding	0.856075580719879	bayes_pls_golite062009
catalytic activity	0.287695754348243	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle