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View Structure Prediction Details

Protein: csx1
Organism: Schizosaccharomyces pombe
Length: 632 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for csx1.

Description E-value Query
Range
Subject
Range
gi|73976783 - gi|73976783|ref|XP_857420.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
425.0 [0..16] [615..36]
PABPC4 - poly(A) binding protein, cytoplasmic 4 (inducible form)
420.0 [0..16] [615..36]
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
420.0 [0..16] [615..36]
gi|109002439 - gi|109002439|ref|XP_001113342.1| PREDICTED: poly A binding protein, cytoplasmic 4 [Macaca mulatta]
CCDS438.1_1 - null
420.0 [0..16] [615..36]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
419.0 [0..16] [615..36]

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Predicted Domain #1
Region A:
Residues: [1-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIDCLYRRS SLFDTSFVPL HSSIPATSKM SASNSDVNAP ISPVVDEGKS ELVSPTLERL  60
   61 VAPFNCSPSS TPLQDVAGVG SKMSDTLWMG DLEPWMDATF IQQLWASLNE PVNVKVMRSK 120
  121 ASSSETLISY CFVQFSSSAA AERALMKYNN TMIPGAHCTF KLNWATGGGI QHNNFVSRDP 180
  181 EFSIFVGDLL PTTEDSDLFM TFRSIYPSCT SAKIIVDPVT GLSRKYGFVR FSSEKEQQHA 240
  241 LMHMQGYLCQ GRPLRISVAS PKSRASIAAD SALGIVPTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.221849
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.63987691433124 bayes_pls_golite062009
nucleic acid binding 4.05055109233024 bayes_pls_golite062009
mRNA binding 3.54495985180603 bayes_pls_golite062009
binding 3.00411894202318 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
1.35163561991147 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription regulator activity 0.884269546056316 bayes_pls_golite062009
DNA binding 0.841333741555926 bayes_pls_golite062009
mRNA 3'-UTR binding 0.599389001184667 bayes_pls_golite062009
poly-pyrimidine tract binding 0.544292786424842 bayes_pls_golite062009
transcription factor activity 0.182209144070426 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [280-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSNRQPNQDL CSMDPLNTTV FVGGLASNLS EKDLQVCFQP FGRILNIKIP FGKGCGFVQY  60
   61 SEKSAAEKAI NTMQGALVGT SHIRLAWGHN TL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1qm9A
Description: Polypyrimidine tract-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.63987691433124 bayes_pls_golite062009
nucleic acid binding 4.05055109233024 bayes_pls_golite062009
mRNA binding 3.54495985180603 bayes_pls_golite062009
binding 3.00411894202318 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
1.35163561991147 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription regulator activity 0.884269546056316 bayes_pls_golite062009
DNA binding 0.841333741555926 bayes_pls_golite062009
mRNA 3'-UTR binding 0.599389001184667 bayes_pls_golite062009
poly-pyrimidine tract binding 0.544292786424842 bayes_pls_golite062009
transcription factor activity 0.182209144070426 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [372-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVSALSQSQS QVSDEGFDRT LSANQIFGMN QSVIGANSGS SNSSGSSLKS APVSPRTAAA  60
   61 QSLLPNSVVS SINGMNSVNF STISPPPLSR SASISPTLSG SGSGLTPLSS HFPSAAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [489-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLVGGQVYPQ SSVLQSSKIN GSAKVQPSVK LPEWLQPFSG NNHNSFATQD LLTRVSSLKL  60
   61 VDDEQPASLN GSAFQARASR PWNLGRERQS SLIDLRHELE QNENGLEKSG FGLNLRGRLP 120
  121 PRSYSTFNCT GQYLQPSLRL SRDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.6067898155184 bayes_pls_golite062009
mRNA binding 3.56033450577296 bayes_pls_golite062009
single-stranded RNA binding 3.03728178586535 bayes_pls_golite062009
eukaryotic initiation factor 4G binding 2.95613613030851 bayes_pls_golite062009
nucleic acid binding 2.91838330515065 bayes_pls_golite062009
poly(A) RNA binding 2.66269581586161 bayes_pls_golite062009
poly-purine tract binding 2.60937924017999 bayes_pls_golite062009
binding 2.12178506555766 bayes_pls_golite062009
protein binding 0.856075580719879 bayes_pls_golite062009
catalytic activity 0.287695754348243 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle