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Protein Overview: pch1

General Information:
Name(s) found: pch1 / SPBC32F12.06 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • cyclin Pch1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 342 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    positive transcription elongation factor complex b [TASLink to PubMed article]
    Biological Process: phosphorylation of RNA polymerase II C-terminal domain [IDALink to PubMed article]
    regulation of RNA elongation from RNA polymerase II promoter [NAS]
    mRNA capping [TASLink to PubMed article]
    protein amino acid phosphorylation [NAS]
    regulation of gene-specific transcription from RNA polymerase II promoter [NAS]
    regulation of cyclin-dependent protein kinase activity [NASLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase regulator activity [NASLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVIKSVPP GSQNTSQWII SKDQLVFTPS ALDGIPLDQE EIQRSKGCNF IINVGLRLKL  60
   61 PQTALATANI YFHRFYLRFS LKNYHYYEVA ATCIFLATKV EDSVRKLRDI VINCAKVAQK 120
  121 NSNVLVDEQT KEYWRWRDVI LYTEEVLLEA LCFDFTVEHP YPYVLSFIKK FVADDKNVTK 180
  181 VAWTYINDST RSIACLLYSP KTIAAAAFQF ALEKNEINLS TTTDGLPVWM EESQVSYEDV 240
  241 KGVLTLIDSL YKKINPSKQA LPIDQKNGSH ASSVAPGTPS SLASVSTQAT PQHQNSSGRT 300
  301 DSFHSLNTET PSKSTVDDQI LSTAAQPKKS SDTDKEMETE AS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..342] PSI-BLAST 43.0 No description for 2pk2A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  8.12427628405368 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  6.12919068656167 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  3.81462270101479 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  2.90083336559452 bayes_pls_golite062009
  • kinase regulator activity
    		•  2.84789294954357 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.795846725429 bayes_pls_golite062009
  • binding
    		•  2.4204867358489 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.04886889839181 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.00665312545368 bayes_pls_golite062009
  • DNA binding
    		•  1.94297811210385 bayes_pls_golite062009
  • protein binding
    		•  1.47106731485576 bayes_pls_golite062009
  • kinase activity
    		•  1.38878672278174 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21921365719206 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.13015830171495 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.12685411405053 bayes_pls_golite062009
  • protein kinase activity
    		•  0.957590284872001 bayes_pls_golite062009
  • transcription factor binding
    		•  0.749278791251235 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.729629809946521 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.567809158275482 bayes_pls_golite062009
  • transferase activity
    		•  0.532488713136535 bayes_pls_golite062009
  • kinase binding
    		•  0.451409627821468 bayes_pls_golite062009
  • enzyme binding
    		•  0.145967754156613 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.138191616709499 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0696060248241566 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle