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Protein Overview: arc2

General Information:
Name(s) found: arc2 / SPAC6F6.10c [Sanger Pombe]
Description(s) found:
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  • pir||T39044 probable Arp2-3 complex subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3121760|sp|O14241.1|ARPC2_SCHPO RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC [NCBI NR]
  • gi|2389000|emb|CAB11733.1| ARP2/3 actin-organizing complex subunit Arc34 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|197305153|pdb|3DWL|I Chain I, Crystal Structure Of Fission Yeast Arp23 COMPLEX LACKING The Arp2 Subunit [NCBI NR]
  • gi|197305147|pdb|3DWL|D Chain D, Crystal Structure Of Fission Yeast Arp23 COMPLEX LACKING The Arp2 Subunit [NCBI NR]
  • gi|19114815|ref|NP_593903.1| ARP2/3 actin-organizing complex subunit Arc34 [Schizosaccharomyces pombe] [NCBI NR]
  • ARP2/3 actin-organizing complex subunit Arc34 [Sanger Pombe]
  • Actin-related protein 2/3 complex subunit 2 OS=Schizosaccharomyces pombe GN=arc2 PE=1 SV=1 [Swiss-Prot]
  • (O14241) Probable ARP2/3 complex 34 kDa subunit (P34-ARC) [Swiss-Prot]
  • ARP2/3 ACTIN-ORGANIZING COMPLEX; INVOLVED IN ACTIN ASSEMBLY AND FUNCTION; S. CEREVISIAE HOMOLOG ARC35 ALSO INVOLVED IN ENDOCYTOSIS: O14241; [pompepVF.fasta]
  • COMPONENT OF THE ARP2/3 ACTIN-ORGANIZING COMPLEX; INVOLVED IN ACTIN ASSEMBLY AND FUNCTION; S. CEREVISIAE HOMOLOGUE ARC35 ALSO INVOLVED IN ENDOCYTOSIS: O14241; [pompepV13]
  • Probable ARP2/3 complex 34 kDa subunit (P34-ARC) [pompep4896]
  • |||ARP2/3 actin-organizing complex [pompepnew.fasta]
  • |arc2|arc34|ARP2/3 actin-organizing complex|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • arp2-3 complex subunit; involved in actin filament assembly [Schizosaccharomyces pombe]gi|2389000|emb|CAB11733.1| SPAC6F6.10c [Schizosaccharomyces pombe]gi|3121760|sp|O14241|AR34_SCHPO Probable ARP2/3 complex 34 kDa subunit (P34-ARC)gi|7492405|pir||T39 [nrdb_11152004_Chlamydomonas]
  • |arc2|arc34|ARP2/3 actin-organizing complex Arc34p subunit|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • |arc2|arc34|ARP2/3 actin-organizing complex subunit Arc34|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC6F6.10c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • ARP2/3 complex 34 kDa subunit (p34-ARC) [nr-271106-contam.fasta]
  • hypothetical protein SPAC6F6.10c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Actin-related protein 2/3 complex subunit 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=arc2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 317 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell division site [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    actin cortical patch [IDALink to PubMed article]
    Arp2/3 protein complex [IDALink to PubMed article]
    Biological Process: Arp2/3 complex-mediated actin nucleation [IDALink to PubMed article]
    actin cortical patch assembly [ICLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSLDYNNIF IYELLTERFS SENPSSIDQV VTDFDGVTFH ISTPEEKTKI LISLSMKCYP  60
   61 ELVNYGTLDL LKQIYGAYVH EPEMGYNFSI LIDLQQLPAT DEEKEQLAMS ISMLKRNVLA 120
  121 APFHRAFTKQ AELADLARKD PENAPMLDKQ ATSQELMAIH YRDEETIVLW PEHDRVTVVF 180
  181 STKFREETDR IFGKVFLQEF VDARRRPAIQ TAPQVLFSYR DPPLEIRDIQ GIQKGDDFGF 240
  241 VTFVLFERHF TPQNREDCIS HIQVFRNTLH FHIKASKAYM HQRMRKRVAD FQKVLNRAKP 300
  301 DVELERKTAT GRSFVRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..317] PSI-BLAST 137.0 ARPC2 (34 kDa subunit)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  6.0922573068519 bayes_pls_golite062009
  • actin filament binding
    		•  5.01990273175321 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.64781612293343 bayes_pls_golite062009
  • binding
    		•  2.16088008530271 bayes_pls_golite062009
  • protein binding
    		•  1.98253629760139 bayes_pls_golite062009
  • structural molecule activity
    		•  1.40122171600941 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.37010524302636 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle