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Protein Overview: fma1

General Information:
Name(s) found: fma1 / SPBC3E7.10 [Sanger Pombe]
Description(s) found:
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  • pir||T40384 probable methionine aminopeptidase 1 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3130036|emb|CAA19013.1| methionine aminopeptidase Fma1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112889|ref|NP_596097.1| methionine aminopeptidase Fma1 (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|13626104|sp|O59730.1|AMPM1_SCHPO RecName: Full=Probable methionine aminopeptidase 1; Short=MetAP 1; Short=MAP 1; AltName: Full=Peptidase M 1 [NCBI NR]
  • methionine aminopeptidase Fma1 [Sanger Pombe]
  • Probable methionine aminopeptidase 1 OS=Schizosaccharomyces pombe GN=SPBC3E7.10 PE=1 SV=1 [Swiss-Prot]
  • (O59730) Probable methionine aminopeptidase 1 (EC 3.4.11.18) (MetAP 1) (MAP 1) (Peptidase M 1) [Swiss-Prot]
  • PUTATIVE METHIONINE AMINOPEPTIDASE: O59730; [pompepVF.fasta]
  • Probable methionine aminopeptidase 1 (EC 3.4.11.18) (MetAP 1) (MAP 1) (Peptidase M 1) [pompep4896]
  • |||putative methionine aminopeptidase [pompepnew.fasta]
  • |||methionine aminopeptidase (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative methionine aminopeptidase [Schizosaccharomyces pombe]gi|3130036|emb|CAA19013.1| SPBC3E7.10 [Schizosaccharomyces pombe]gi|7492720|pir||T40384 probable methionine aminopeptidase 1 - fission yeast (Schizosaccharomyces pombe)gi|13626104|sp|O59730 [nrdb_11152004_Chlamydomonas]
  • |||methionine aminopeptidase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • |fma1||methionine aminopeptidase Fma1 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC3E7.10 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC3E7.10 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Probable methionine aminopeptidase 1 (MetAP 1) (MAP 1) (Peptidase M 1) [nr-271106-contam.fasta]
  • Methionine aminopeptidase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fma1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosolic ribosome [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: protein initiator methionine removal [ISS]
    proteolysis [ISSLink to PubMed article]
    Molecular Function: metalloexopeptidase activity [IEA]
    aminopeptidase activity [ISSLink to PubMed article]
    cobalt ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATEIAKHIC CGIDCNNEAD RLQCPKCLND GVKSYFCGQE CFRNSWNIHK HLHRPPNVEK  60
   61 REDGTYNPFP KFHFAGSLKP VYPLSPIRKV PPHIKRPDYA KTGVSRSEQI EGRSFKLKRL 120
  121 TPKEQEGMRK VCRLGREVLD AAAAAVRPGT TTDELDSIVH NACIERDCFP STLNYYAFPK 180
  181 SVCTSVNEII CHGIPDQRPL EDGDIVNIDV SLYHNGFHGD LNETYYVGDK AKANPDLVCL 240
  241 VENTRIALDK AIAAVKPGVL FQEFGNIIEK HTNSITEKQI SVVRTYCGHG INQLFHCSPS 300
  301 IPHYSHNKAP GIARPGMTFT IEPMLTLGPA RDITWPDDWT SSTASGRCSA QFEHTLLVTE 360
  361 TGCEVLTARL PNSPGGPLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..57] MSA 3.107992 View MSA. Confident ab initio structure predictions are available.
    2 View Details [58..379] PSI-BLAST 79.69897 Crystal structure of Human Methionine Aminopeptidase Type I with a third cobalt in the active site


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle