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Protein Overview: SPAC24C9.06c

General Information:
Name(s) found: SPAC24C9.06c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • aconitate hydratase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    cytosol [ISSLink to PubMed article]
    Biological Process: glutamate metabolic process [ISSLink to PubMed article]
    citrate metabolic process [ISSLink to PubMed article]
    propionate metabolic process [ISSLink to PubMed article]
    tricarboxylic acid cycle [ISSLink to PubMed article]
    Molecular Function: iron ion binding [IEA]
    4 iron, 4 sulfur cluster binding [IEA]
    iron-sulfur cluster binding [IEA]
    aconitate hydratase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSRIFTQST LRSFSCAPVA ANIDAKKVAM SNFEKNKFIN YQRIKDNLEI VKKRLNRPLT  60
   61 YSEKILYGHL DDPVNQDIER GVSYLKLRPD RVACQDATAQ MAILQFMSAG MPEVAVPVTV 120
  121 HCDHLIEAYE GGPIDLERAN VTNKEVYDFL QTACAKYNIG FWRPGSGIIH QIVLENYAFP 180
  181 GGLLIGTDSH TPNAGGLGMV AIGVGGADAV DVMANLPWEL KCPKVIGVKL TGQLKGWTSP 240
  241 KDVILKVAGI LTVKGGTGAI VEYFGPGVES LSCTGMGTIC NMGAEIGATT SIFPFNPRMS 300
  301 EYLRATNRSA IADYAEEFAP IIAADENAHY DQIIEIDLNT LEPHLNGPFT PDLATPISKF 360
  361 KEAVKKNDWP QELKVGLIGS CTNSSYEDMS RAASICQQAI DKGIKTKSLF TITPGSEQVR 420
  421 ATLTRDGQLD TMRKAGGIVL ANACGPCIGQ WKRTDVKKGE KNSIVTSYNR NFTGRNDANP 480
  481 ATHAFVTSPD IVTAMVFSGD MNFNPLTDTL KDKDGNDFKF EPPTGAGLPS KGYDPGSNTY 540
  541 VAPSSVNVKD VAIDPHSKRL QRLTPFKKWD GKDMKGLKIL IKAKGKCTTD HISAAGPWLK 600
  601 YRGHLQNISN NYMIGAINAE NGEANKLKDQ LTGEYKTVPN VAIDYRDHGI RWVTLGEQNF 660
  661 GEGSSREHAA LEPRYLGGAA VITKSFARIH ETNLKKQGLL PLTFADPAAY DKISPFDTVD 720
  721 IDGLTTFAPG KPLTLVVHPA DGSAEWSTKL NHTFNKDQIE WFKAGSALNH MANMHKQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..778] PSI-BLAST 1000.0 STRUCTURE OF ACTIVATED ACONITASE. FORMATION OF THE (4FE-4S) CLUSTER IN THE CRYSTAL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-isopropylmalate dehydratase activity
    		•  11.6597692115322 bayes_pls_golite062009
  • aconitate hydratase activity
    		•  5.86356477922338 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.93956285477489 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.25736437672211 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  2.08349115784849 bayes_pls_golite062009
  • hydro-lyase activity
    		•  2.04845291489052 bayes_pls_golite062009
  • lyase activity
    		•  2.0080619912194 bayes_pls_golite062009
  • metal cluster binding
    		•  1.70706327499066 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.70706327499066 bayes_pls_golite062009
  • binding
    		•  1.67914740974449 bayes_pls_golite062009
  • DNA binding
    		•  1.6436451615422 bayes_pls_golite062009
  • iron-responsive element binding
    		•  1.1980380564483 bayes_pls_golite062009
  • iron ion binding
    		•  1.12961684198784 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  1.11810757572823 bayes_pls_golite062009
  • mRNA binding
    		•  1.0310744464034 bayes_pls_golite062009
  • structural molecule activity
    		•  0.870913754566634 bayes_pls_golite062009
  • RNA binding
    		•  0.42311333660604 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.342428816025605 bayes_pls_golite062009
  • protein binding
    		•  0.232638130896339 bayes_pls_golite062009
  • cation binding
    		•  0.0272064751959212 bayes_pls_golite062009
  • metal ion binding
    		•  0.0272064751959212 bayes_pls_golite062009
  • ion binding
    		•  0.0228992031160024 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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