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Protein Overview: RunxB-PB

General Information:
Name(s) found: RunxB-PB / FBpp0288879 [FlyBase]
Description(s) found:
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  • gi|7295584|gb|AAF50894.1| CG42267, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24643542|ref|NP_608398.1| CG42267, isoform B [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\RunxB (CG42267, FBgn0259162). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:20404788..20437040. It has the cytological map location 19D3. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cellular process. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG15455-PA translation from_gene[CG15455 CG15455 FBgn0031121] seq_release:3 mol_weight=34401 cds_boundaries:(X:20,213,679..20,226,678[+]) aa_length:306 transcript_info:[CG15455-RA seq_release:3] gene_info:[gene symbol:CG15455 FBgn0031121 gene_boundari [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VRA8) CG15455 protein [DrosMelano7227.FASTAC.txt]
  • (AE003571) CG15455 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG15455-PA [Drosophila melanogaster]gi|24643542|ref|NP_608398.1| CG15455-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(20411908..20412297,20412855..20413071,20424597..20424910); ID=FBpp0288879; name=CG42267-PB; parent=FBgn0259162,FBtr0299604; dbxref=FlyBase_Annotation_IDs:CG42267-PB,FlyBase:FBpp0288879,REFSEQ:NP_608398,GB_protein:AAF50894; MD5=729 [fly-100309-contam.fasta]
  • CG15455-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(20411908..20412297,20412855..20413071,20424597..20424910); ID=FBpp0288879; name=CG42267-PB; parent=FBgn0259162,FBtr0299604; dbxref=FlyBase_Annotation_IDs:CG42267-PB,FlyBase:FBpp0288879,REFSEQ:NP_608398,GB_protein:AAF50894; MD5=729fd2251bf44da4ba39a429220a36d6; length=306; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(20411908..20412297,20412855..20413071,20424597..20424910); ID=FBpp0288879; name=RunxB-PB; parent=FBgn0259162,FBtr0299604; dbxref=FlyBase_Annotation_IDs:CG42267-PB,FlyBase:FBpp0288879,REFSEQ:NP_608398,GB_protein:AAF50894; MD5=729fd2251bf44da4ba39a429220a36d6; length=306; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • RunxB, isoform B OS=Drosophila melanogaster GN=RunxB PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC][IEA][NAS]
    Biological Process: regulation of transcription, DNA-dependent [IEA][ISS]
    regulation of transcription [IEA]
    cellular process [IMP]
    Molecular Function: ATP binding [IEA]
    transcription factor activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHISAEVSST TSNQIQQQQQ QHQQQQQHQL LQHQQQQTAT TTTTKRRNAE SSASSNNNNN  60
   61 NNTSTTNNNN TNNNNNSTTN NNNNNNNNNV KTKPVDTSPY LTPENLIERT VDVLLAEHPG 120
  121 ELVKTGSPHV VCTTLPTHWR SNKTLPIAFK VLALGEVMDG TIVTIRAGND ENFCGELRNC 180
  181 TAVMKNQVAK FNDLRFVGRS GRGKSFTLTI VISTNPIQIA TYTKAIKVTV DGPREPRSKV 240
  241 RHQGFHPFAF GPQRFGPDPL MAGLPFKLPG KRKRWRRFRG NQGFGRLKRK HRRHTERNSG 300
  301 YSISLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] deduced N/A No confident structure predictions are available.
    2 View Details [97..306] PSI-BLAST 77.69897 Acute myeloid leukemia 1 protein (AML1), RUNT domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.13591399970354 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.54158309583174 bayes_pls_golite062009
  • DNA binding
    		•  0.53363287856737 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.3602964037518 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle