YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RunxB-PB
Organism: Drosophila melanogaster
Length: 306 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RunxB-PB.

Description E-value Query
Range
Subject
Range
gi|83405621 - gi|83405621|gb|AAI10829.1| RUNX1 protein [Homo sapiens]
366.0 [0..53] [303..2]

Back

Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHISAEVSST TSNQIQQQQQ QHQQQQQHQL LQHQQQQTAT TTTTKRRNAE SSASSNNNNN  60
   61 NNTSTTNNNN TNNNNNSTTN NNNNNNNNNV KTKPVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSPYLTPENL IERTVDVLLA EHPGELVKTG SPHVVCTTLP THWRSNKTLP IAFKVLALGE  60
   61 VMDGTIVTIR AGNDENFCGE LRNCTAVMKN QVAKFNDLRF VGRSGRGKSF TLTIVISTNP 120
  121 IQIATYTKAI KVTVDGPREP RSKVRHQGFH PFAFGPQRFG PDPLMAGLPF KLPGKRKRWR 180
  181 RFRGNQGFGR LKRKHRRHTE RNSGYSISLK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.69897
Match: 1e50A
Description: Acute myeloid leukemia 1 protein (AML1), RUNT domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13591399970354 bayes_pls_golite062009
nucleic acid binding 0.54158309583174 bayes_pls_golite062009
DNA binding 0.53363287856737 bayes_pls_golite062009
transcription regulator activity 0.3602964037518 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle