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Protein Overview: FBpp0309369, Tsf1-PA

General Information:
Name(s) found: FBpp0309369 [FlyBase]
Tsf1-PA / FBpp0074331 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=X:join(18281982..18282081,18282157..18282399,18282607..18283702,18283765..18284149,18284213..18284314); ID=FBpp0309369; name=Tsf1-PB; parent=FBgn0022355,FBtr0340423; dbxref=FlyBase:FBpp0309369,FlyBase_Annotation_IDs:CG6186-PB; MD5=a22e31f8a4c6539a0472ed7142db086e; length=641; release=r5.56; species=Dmel; [FlyBase]
  • The gene Transferrin 1 is referred to in FlyBase by the symbol Dmel\Tsf1 (CG6186, FBgn0022355). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18281965..18284377. It has the cytological map location 17A9. Based on sequence similarity, it is predicted to have molecular function</span>: iron ion transmembrane transporter activity; ferric iron binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cellular iron ion homeostasis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    Biological Process: cellular iron ion homeostasis [ISS]
    iron ion transport [IEA][NAS]
    defense response [NAS]
    Molecular Function: ferric iron binding [ISS]
    iron ion transmembrane transporter activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSPHKTHTW LPLAVAALLL ILGPQSSLAE EPIYRLCVPQ IYLAECQQLL ADPSEAGIRM  60
   61 ECVAGRDRVD CLELIEQRKA DVLATEPEDM YIAYHRKNED YRVISEIRTQ QDKDAAFRYE 120
  121 GIILVKKDSP IRTLQQLRGA KSCHTGFGRN VGYKIPITKL KNTHVLKVSA DPQISATERE 180
  181 LKSLSEFFTQ SCLVGTYSTH PETDRLLKKK YANLCALCEK PEQCNYPDKF SGYDGAIRCL 240
  241 DKGQGEVAFS KVQYIKKYFG LPGAGPDAPP AEGNPENFEY LCEDGTRRPV TGPACSWAQR 300
  301 PWSGYISNEQ AVHNSEQLHQ LQSRLERFFA NGLQAQNKDA AAHLLIQPNA VYHSKDAAID 360
  361 PKVYLERAGY KDVIERDGSA IRKIRLCAQN DDEFAKCQAL HQAAYARDAR PELECVQSTD 420
  421 CVVALTKKEA DLTIVRATGY ADARSNQLQP IVYEQRAQDD VLVAVAAPGV TREALQKASI 480
  481 KFNENCERSR AAAALLNKRR GLDACRVSSS DDGEVQIVPA SELEKHKDAQ LVCPSLERRP 540
  541 VTDFRDCNVD VQLPRAIFIR SDTTSVEQET VKHLFSLISD KFGARGKLVD VFALFGEFQK 600
  601 GKKNVYFNDK AVQLTTELKN EIQNEQIYTD LQCNANKIAK Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..641] PSI-BLAST 180.0 No description for 2havA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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