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Protein Overview: gi|28571249, gi|...

General Information:
Name(s) found: gi|28571249 [NCBI NR]
gi|28571245 [NCBI NR]
gi|28381645 [NCBI NR]
gi|28381644 [NCBI NR]
Description(s) found:
Found 12 descriptions.
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  • gi|28571249|ref|NP_788926.1| glutathione synthetase, isoform D [Drosophila melanogaster] [NCBI NR]
  • gi|28571245|ref|NP_788925.1| glutathione synthetase, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|28381645|gb|AAO41700.1| glutathione synthetase, isoform D [Drosophila melanogaster] [NCBI NR]
  • gi|28381644|gb|AAO41699.1| glutathione synthetase, isoform C [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: glutathione biosynthetic process [IEA]
    response to DNA damage stimulus [IMP]
    Molecular Function: ATP binding [IEA]
    glutathione synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDANTAVL RNCIRLPLAE DELLEVTAKA KDYAIMHGAA MRSKTAFSPD SLNFAPFVLV  60
   61 PSSFPRKEFE KAVALQPIIN RLMHNVAHDE EFITTTLAET IKVDEFTANL FNIYRKVLAH 120
  121 GFTQKTSLGM LRSDLMLESG CPELSPRALR TAAGEDRGQD AGAAVGQIAG ANGAAGVGTA 180
  181 AGTGSKEEEH REVQLSRVTK EPERRATGAQ SAYCCWKQVE INTIASGFGH LGPASKTIQR 240
  241 FVLSELGHAD KLHNMPDNNA LAGLCDGMVK AWDIYAKPQA VILFIIEDVS YNICDQRFHE 300
  301 FYIRETYPHI KVLRRTLTEV HREGKLGQSK ELLLGSQEVA VIYFRAGYEP GHYHSQADWD 360
  361 ARYLMETSLA IKCPSIHYHL AGTKKVQQAL AQPAVLERFI NDPEEIKAVG KIFTGLYSLD 420
  421 DNEAGNASYE MALRTPERFV LKPQREGGGN NRMSRVERSA WILMDLIHPP LTKGYMVRPG 480
  481 GDMPPQIVDM VSELGIFGVV IGDAEHIVHN YQAGHMLRTK LSTANEGGVA AGLGALDSPY 540
  541 LIDSDDEDEQ K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..551] PSI-BLAST 168.0 Eukaryotic glutathione synthetase, substrate-binding domain; Eukaryotic glutathione synthetase ATP-binding domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutathione synthase activity
    		•  3.36797779177268 bayes_pls_golite062009
  • catalytic activity
    		•  2.87139587563481 bayes_pls_golite062009
  • ligase activity
    		•  1.70071261805297 bayes_pls_golite062009
  • succinate-CoA ligase activity
    		•  0.970113655642181 bayes_pls_golite062009
  • CoA-ligase activity
    		•  0.85407001746442 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  0.79517718342104 bayes_pls_golite062009
  • glutathione binding
    		•  0.65617009195909 bayes_pls_golite062009
  • succinate-CoA ligase (ADP-forming) activity
    		•  0.61662787854529 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.463643664297841 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  0.45881977344533 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.28951341378787 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle