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Protein Overview: xmas-2-PA

General Information:
Name(s) found: xmas-2-PA / FBpp0074178 [FlyBase]
Description(s) found:
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  • gi|29337241|sp|Q9U3V9.3|XMAS2_DROME RecName: Full=Protein xmas-2 [NCBI NR]
  • gi|24642732|ref|NP_728054.1| xmas-2 [Drosophila melanogaster] [NCBI NR]
  • gi|22832432|gb|AAN09434.1| xmas-2 [Drosophila melanogaster] [NCBI NR]
  • (Q9U3V9) Xmas-2 protein [Swiss-Prot]
  • Protein xmas-2 OS=Drosophila melanogaster GN=xmas-2 PE=1 SV=3 [Swiss-Prot]
  • The gene xmas-2 is referred to in FlyBase by the symbol Dmel\xmas-2 (CG32562, FBgn0028974). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17048143..17053339. It has the cytological map location 15E7-15F1. It is reported to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: poly(A)+ mRNA export from nucleus. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG32562-PA translation from_gene[CG32562 xmas-2 FBgn0028974] seq_release:3 mol_weight=158182 cds_boundaries:(X:16,885,940..16,890,173[-]) aa_length:1370 transcript_info:[CG32562-RA seq_release:3] gene_info:[gene symbol:xmas-2 synonyms:[CG8919] FBgn002 [hmr_yeast5_DM3-1_pombe.fasta]
  • CG32562-PA [Drosophila melanogaster]gi|24642732|ref|NP_728054.1| CG32562-PA [Drosophila melanogaster]gi|29337241|sp|Q9U3V9|XMS2_DROME Xmas-2 protein [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(17049011..17051545,17051606..17053139,17053204..17053247); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,G [fly-100309-contam.fasta]
  • CG32562-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Protein xmas-2 [nr-271106-contam.fasta]
  • xmas-2 CG32562-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(17049011..17051545,17051606..17053139,17053204..17053247); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(17049011..17051545,17051606..17053139,17053204..17053247); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=X:complement(17049011..17051545,17051606..17053139,17053204..17053247); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434,FlyMine:FBpp0074178,modMine:FBpp0074178; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(17159171..17159214,17157573..17159106,17154978..17157512)); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434,FlyMine:FBpp0074178,modMine:FBpp0074178; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(17159171..17159214,17157573..17159106,17154978..17157512)); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434,FlyMine:FBpp0074178,modMine:FBpp0074178; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0074178 type=protein; loc=X:complement(join(17159171..17159214,17157573..17159106,17154978..17157512)); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434,FlyMine:FBpp0074178,modMine:FBpp0074178; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(17159171..17159214,17157573..17159106,17154978..17157512)); ID=FBpp0074178; name=xmas-2-PA; parent=FBgn0028974,FBtr0074404; dbxref=FlyBase:FBpp0074178,FlyBase_Annotation_IDs:CG32562-PA,GB_protein:AAN09434.1,REFSEQ:NP_728054,GB_protein:AAN09434,UniProt/Swiss-Prot:Q9U3V9,FlyMine:FBpp0074178,modMine:FBpp0074178; MD5=9fcc7f49e2be24fbfa5dde9776478c2e; length=1370; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1370 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: embryonic development [NAS]
    oogenesis [NAS]
    spermatogenesis [NAS]
    poly(A)+ mRNA export from nucleus [IMP]
    Molecular Function: nucleic acid binding [IEA]
    mRNA binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPRPGGYN YKTLLCRNIP ELFLDKYVAR SHFGRFGTLV NFVLRPRRMT CTVSYASEDE  60
   61 AARALLDGAS FQGHLFDISY ADNETAPAQK TEEWVDPDIQ AELSALQSGW RNEYGSGKPI 120
  121 KKPQNGSSGS GGSSMLPAIP VGPATAPVSR DRTPAQLRDL ENMMRRPAHT SEEKFSVLDA 180
  181 RDKLLRLNRT QHKLSGATQG HCADMCPEKE RVLREFQRQV AYYELQPGSD ELICHERALK 240
  241 QYSRSSADQE TPLPHELRNE TALHMTMSYL MHEIMDISER QDPQSHMGDW FHFVWDRTRS 300
  301 IRKEITQQEL CSLGAVKLVE QCARFHIHCA ARLVDADPSV FDSKINAENL TKCLQTLKYM 360
  361 YHDLRIKGVP CPKEAEFRGY IVLLNLADAN FLWDIGQLPA ELQSCPEVRQ AIQFYLALQD 420
  421 TNFVRFFQLL ADKDTSYLSA CILVNYFTRL RVLGLHRLIQ AYRSPRKDEV SSLPLSYIAE 480
  481 LLSFASEQEA ADFVQHYGLQ INEAGRVVLS RMHTVETEYK LPRQYELVEV KRVKSVGEVV 540
  541 SGEPLPPRDL YLNHRPHNSF DDYGMLKSIA WTAKDQLAGM QQEEMQPQMP SQPPAVSKHS 600
  601 DTLFKVPMQP DGTAAGFGVF AAAAVPPASS IDGFSFVLPK SRAQEFQEQA PATQQRRAQE 660
  661 EAKHQALQVA IAAAKKREAE LMAIHEAKVA EAERVRQQKL RERQEQQRRQ QQELEEQRQR 720
  721 EQEKLQLEKE RQLKLEQLFF VQQQEREAHK QTRTLELYQE IFQDTLAEIC QSEFMSHSRA 780
  781 CRSYESMLDS ITRDLVERQM EQSIYELGVM RVCIRRWRKY RRTQQEKDTL FNQLPLSFGA 840
  841 ENPEGVVNKR SMEDSLRLSR RYRLGEPCDY GKLLAGLEEH SWLKLDLWHV LDKCLPVAQP 900
  901 GARRFYKLLI SLSGGQEGLQ LNCDLDRGLL QQPQSPDARF VDGGYIRGFS QGIGLSVMKI 960
  961 RDDDHDWKAT DLAEANGIIC LIGLDDIRLL PDRLKPLLQA SRCHDVAVIV QHPANTAFVQ1020
 1021 PDIPLQELCL RSFNIFRLRK SGNNRQRLMI ALESAVKFLA KATERKRVGH LHQVETREYL1080
 1081 LVNLGSELFR RLKYAAEHDT AIRSDTQLNP QRCVDLFNEA VHRLQLVAGE DLSDWPQFPE1140
 1141 ELRVFVQPLP IESSLNTNRL EHFEPGWHLP ERRQRIVQLL ERCKLPKMPV LPRSSSLAEA1200
 1201 QCQWVLDYAQ ISQQEDCVEQ IALQAIKILQ YDTDDYLNFV EYLAGERMQY ILRQERNPPQ1260
 1261 GIVYNTKTLK RRFLSAWYYE FREPQIYEPV PAEENAQMLE KQPSSQAEVQ QLDFDEITSK1320
 1321 AEAVLKRFHQ RQDERHTLRE LNRSHKSRKR RDASDHKHAS KHKRKRSKSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..121] FFAS03 3.14 Solution structure of the second RNA binding domain from hypothetical protein BAB23448
    2 View Details [122..287] deduced N/A No confident structure predictions are available.
    3 View Details [288..499] deduced N/A No confident structure predictions are available.
    4 View Details [500..602] PSI-BLAST 3.69897 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
    5 View Details [603..959] PSI-BLAST 20.045757 Heavy meromyosin subfragment
    6 View Details [960..1066] PSI-BLAST 6.39794 No description for 2dfsA was found.
    7 View Details [1067..1289] deduced N/A No confident structure predictions are available.
    8 View Details [1290..1370] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  3.07267754227671 bayes_pls_golite062009
  • binding
    		•  2.14220509119821 bayes_pls_golite062009
  • mRNA binding
    		•  1.8272533737271 bayes_pls_golite062009
  • protein binding
    		•  0.825412428838605 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.698120867472476 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.0341340403989611 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle