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Protein Overview: Cap-PB

General Information:
Name(s) found: Cap-PB / FBpp0074066 [FlyBase]
Description(s) found:
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  • gi|24642557|ref|NP_727988.1| Chromosome-associated protein, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|22832386|gb|AAN09411.1| Chromosome-associated protein, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|115646462|gb|ABJ17066.1| IP16426p [Drosophila melanogaster] [NCBI NR]
  • The gene Chromosome-associated protein is referred to in FlyBase by the symbol Dmel\Cap (CG9802, FBgn0015615). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16483035..16487462. It has the cytological map location 14F1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; ATP binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: sister chromatid cohesion. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG9802-PB translation from_gene[CG9802 Cap FBgn0015615] seq_release:3 mol_weight=123223 cds_boundaries:(X:16,320,363..16,323,598[-]) aa_length:1054 transcript_info:[CG9802-RB seq_release:3] gene_info:[gene symbol:Cap FBgn0015615 gene_boundaries:(X:16, [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8IR12) CG9802-PB [DrosMelano7227.FASTAC.txt]
  • CG9802-PB, isoform B [Drosophila melanogaster]gi|24642557|ref|NP_727988.1| CG9802-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(16483373..16483585,16483660..16486611); ID=FBpp0074066; name=Cap-PB; parent=FBgn0015615,FBtr0074291; dbxref=FlyBase:FBpp0074066,GB_protein:AAN09411.1,FlyBase_Annotation_IDs:CG9802-PB,REFSEQ:NP_727988,GB_protein:AAN09411; MD5 [fly-100309-contam.fasta]
  • IP16426p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Chromosome-associated protein CG9802-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG9802-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(16483373..16483585,16483660..16486611); ID=FBpp0074066; name=Cap-PB; parent=FBgn0015615,FBtr0074291; dbxref=FlyBase:FBpp0074066,GB_protein:AAN09411.1,FlyBase_Annotation_IDs:CG9802-PB,REFSEQ:NP_727988,GB_protein:AAN09411; MD5=e2c93837bf9448598ed1289625b2dea1; length=1054; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(16483373..16483585,16483660..16486611); ID=FBpp0074066; name=Cap-PB; parent=FBgn0015615,FBtr0074291; dbxref=FlyBase:FBpp0074066,GB_protein:AAN09411.1,FlyBase_Annotation_IDs:CG9802-PB,REFSEQ:NP_727988,GB_protein:AAN09411; MD5=e2c93837bf9448598ed1289625b2dea1; length=1054; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Chromosome-associated protein, isoform B OS=Drosophila melanogaster GN=Cap PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(16483373..16483585,16483660..16486611); ID=FBpp0074066; name=Cap-PB; parent=FBgn0015615,FBtr0074291; dbxref=FlyBase:FBpp0074066,GB_protein:AAN09411.1,FlyBase_Annotation_IDs:CG9802-PB,REFSEQ:NP_727988,GB_protein:AAN09411,FlyMine:FBpp0074066,modMine:FBpp0074066; MD5=e2c93837bf9448598ed1289625b2dea1; length=1054; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1054 amino acids

    Gene Ontology:
    Cellular Component: cohesin complex [ISS][NAS]
    Biological Process: sister chromatid cohesion [ISS]
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATAADSYRL KLLREVAGTR VYDERKEESL NLLRETDSKV EKISEYLKTI EDRLQTLEEE  60
   61 KEELKEYQKW DKTRRTLEYI RYETELKDTK KALDELQLQR KSSSDKKKIY NIEIQKAQEK 120
  121 IKDVQKNLKE AKKKVQSTKE ERSVLMTEQQ QLLREKTKLD LTIVDLNDEV QGDNKSKERA 180
  181 DQELKNLKVT IAEREKELDD VKPKYEAMKR KEEDCSRELQ LKEQKRKELY AKQGRGSQFS 240
  241 SREDRDKWIT NELKSISKQT RDKIAHHAKL VEDLKKDATS EKDLGQKIEE HSSELEQLRL 300
  301 QIDEHNKKYY ELKKTKDQHQ SMRNELWRKE TQMTQQLQTH KEELSRADQA LRSMAGKPIL 360
  361 NGCDSVRKVL DSFVERGGQS AEIARAYYGP VIENFSCDKT IYTAVEVTAA NRLFHHIVES 420
  421 EYEGTQILKE MNKLKLPGEV TFMPLNRLQV KIHDYPDDPD SIPMISKLKY DEQHDKALRY 480
  481 IFGKTLICRN LERATELAKS TGLDCVTLDG DQVSSKGSLT GGYFNTSRSR LEMQKKRTEY 540
  541 TSQIAEFEKK LSKLRNELKS TENNINSIVS EMQKTETKQG KSKDVFEKVQ GEIRLMKEEL 600
  601 VRIEQYRAPK ERSLAQCKAS LESMTSTKSS LEAELKQELM STLSSQDQRE IDQLNDDIRR 660
  661 LNQENKEAFT QRMQFEVRKN KLDNLLINNL FRRRDELIQA LQEISVEDRK RKLNNCKTEL 720
  721 VSAEKRIKKV NSDLEEIEKR VMEAVQLQKE LQQELETHVR KEKEAEENLN KDSKQLEKWS 780
  781 TKENMLNEKI DECTEKIASL GAVPLVDPSY TRMSLKNIFK ELEKANQHLK KYNHVNKKAL 840
  841 DQFLSFSEQK EKLYRRKEEL DIGDQKIHML IQSLEMQKVE AIQFTFRQVA QNFTKVFKKL 900
  901 VPMGAGFLIL KTKDNEGDEM EKEVENSDAF TGIGIRVSFT GVEAEMREMN QLSGGQKSLV 960
  961 ALALIFSIQK CDPAPFYLFD EIDQALDAMH RKAVANMIHE LSDTAQFITT TFRPELLENA1020
 1021 HKFYGVRFRN KVSHIDCVTR EEAKDFVEDD STHA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..340] PSI-BLAST 17.69897 Heavy meromyosin subfragment
    2 View Details [341..548] FFAS03 4.72 Smc hinge domain
    3 View Details [549..878] FFAS03 2.49 Tropomyosin
    4 View Details [879..1054] PSI-BLAST 22.30103 Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.91859588671053 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  1.04211475755928 bayes_pls_golite062009
  • protein binding
    		•  1.02696508439754 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.832846345187777 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.76561882762468 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.734314999998814 bayes_pls_golite062009
  • DNA binding
    		•  0.693468729072494 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.489361130553895 bayes_pls_golite062009
  • DNA secondary structure binding
    		•  0.370893450957454 bayes_pls_golite062009
  • catalytic activity
    		•  0.265320175609019 bayes_pls_golite062009
  • ATP binding
    		•  0.161090462621035 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.132019153736693 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.123699115804833 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.00495036379814584 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle