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Protein Overview: Pros28.1-PA

General Information:
Name(s) found: Pros28.1-PA / FBpp0073989 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • The gene Proteasome 28kD subunit 1 is referred to in FlyBase by the symbol Dmel\Pros28.1 (CG3422, FBgn0004066). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16170305..16171621. It has the cytological map location 14B7. Based on sequence similarity, it is predicted to have molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 249 amino acids

    Gene Ontology:
    Cellular Component: proteasome core complex [ISS]
    proteasome core complex, alpha-subunit complex [IEA]
    proteasome complex [NAS]
    Biological Process: response to DNA damage stimulus [IMP]
    ubiquitin-dependent protein catabolic process [IEA][NAS]
    Molecular Function: endopeptidase activity [ISS][NAS]
    threonine-type endopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRYDRAVT IFSPDGHLLQ VEYAQEAVRK GSTAVGVRGA NCVVLGVEKK SVAQLQEDRK  60
   61 VRKICMLDNH VVMAFAGLTA DARIMINRAQ VECQSHRLNV EDPVTLEYIT RFIAQLKQKY 120
  121 TQSNGRRPFG ISCLIGGFDA DGSAHLFQTE PSGIFYEYKA NATGRSAKVV REFFEKSYRE 180
  181 EEVANEHGAV KLAIRALLEV AQSGQNNLEV AIMENGKPLK MLDTDVITDY VKIIEKEKEE 240
  241 ELEKKKQKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..249] PSI-BLAST 69.045757 Proteasome alpha subunit (non-catalytic)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle