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Protein Overview: CG12539-PA

General Information:
Name(s) found: CG12539-PA / FBpp0073804 [FlyBase]
Description(s) found:
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  • gi|24642035|ref|NP_572976.1| CG12539 [Drosophila melanogaster] [NCBI NR]
  • gi|22832247|gb|AAF48394.2| CG12539 [Drosophila melanogaster] [NCBI NR]
  • gi|18447491|gb|AAL68308.1| RE49901p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12539 (CG12539, FBgn0030586). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14736650..14738873. It has the cytological map location 12F5. Based on sequence similarity, it is predicted to have molecular function</span>: glucose dehydrogenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: alcohol metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG12539-PA translation from_gene[CG12539 CG12539 FBgn0030586] seq_release:3 mol_weight=69613 cds_boundaries:(X:14,573,813..14,575,746[-]) aa_length:626 transcript_info:[CG12539-RA seq_release:3] gene_info:[gene symbol:CG12539 FBgn0030586 gene_boundari [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8SXY8) RE49901p (CG12539 protein) [DrosMelano7227.FASTAC.txt]
  • CG12539-PA [Drosophila melanogaster]gi|18447491|gb|AAL68308.1| RE49901p [Drosophila melanogaster]gi|24642035|ref|NP_572976.1| CG12539-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(14736829..14738558,14738615..14738765); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394 [fly-100309-contam.fasta]
  • CG12539-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE49901p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(14736829..14738558,14738615..14738765); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(14736829..14738558,14738615..14738765); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG12539 OS=Drosophila melanogaster GN=CG12539 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(14736829..14738558,14738615..14738765); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394,FlyMine:FBpp0073804,modMine:FBpp0073804; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(14844582..14844732,14842796..14844525)); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394,FlyMine:FBpp0073804,modMine:FBpp0073804; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(14844582..14844732,14842796..14844525)); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394,FlyMine:FBpp0073804,modMine:FBpp0073804; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • RE49901p OS=Drosophila melanogaster GN=CG12539 PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0073804 type=protein; loc=X:complement(join(14844582..14844732,14842796..14844525)); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394,FlyMine:FBpp0073804,modMine:FBpp0073804; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(14844582..14844732,14842796..14844525)); ID=FBpp0073804; name=CG12539-PA; parent=FBgn0030586,FBtr0073987; dbxref=FlyBase:FBpp0073804,FlyBase_Annotation_IDs:CG12539-PA,GB_protein:AAF48394.2,REFSEQ:NP_572976,GB_protein:AAF48394,UniProt/TrEMBL:Q8SXY8,FlyMine:FBpp0073804,modMine:FBpp0073804; MD5=70c622bf51d87641d0451c6ed5587e0f; length=626; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 626 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: alcohol metabolic process [IEA]
    Molecular Function: FAD binding [IEA]
    glucose dehydrogenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSTQISQLF LLLHLLIFTT VARGDVNRLV LDQLNQVGLV NLIEQATRPN VPRDLSNYDF  60
   61 IVIGAGAAGC TLAARLSENP QVSVALIEAG GVENIAHLTP VVAGYLQQTS SNWGYKSVPQ 120
  121 KLSCHGMNNN ECALPRGKIL GGTSSINYMI YNRGNRRDFD AWAAAGNPGW SYDEVLPYFL 180
  181 RSEHAQLQGL EQSPYHNHSG PLSVEYVRFR SQMVDAFVEA SVESGLPRTD YNGESQLGVS 240
  241 YVQANTLNGR RHSAYSAYIK PVRDLRSNLQ IFTFSQVTRI LIDEATKSAY GVEFHYKNKA 300
  301 YTFKARKEVI LSAGSFNSPQ LLMLSGIGPE DNLRGIGIPL IKALPVGKRM FDHMCHFGPT 360
  361 FVTNTTGQTT FTSRVTPAEL ISFLLAGNPA TRMSSIGGVE ALAFLKTQRS NLPNDWPDIE 420
  421 LIMVTGSLAS DEGTGLKLGA NFKDEIYDRM YRELAQAQQD HFTLLIMQFH PKSVGRLWLK 480
  481 DRNPLGWPKI DPKYFVAEED VEYLLDGIKA SLRIIEMPAM QRIGARLLKR TVPGCEGHQF 540
  541 ASDDYWRCSI RTLSYTLHHQ VATCRMGAES DPTTVVNHQL KVHGVRKLRV VDTSIIPFPP 600
  601 TAHTNAAAFM IGEKAADMIR TDWELI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..626] PSI-BLAST 87.39794 Glucose oxidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • choline dehydrogenase activity
    		•  4.66965094791663 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  4.10319574017291 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.3417445147889 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  1.47575323060551 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  1.34149762265767 bayes_pls_golite062009
  • glucose dehydrogenase activity
    		•  1.30840878956762 bayes_pls_golite062009
  • transporter activity
    		•  1.29839290134235 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07862908893913 bayes_pls_golite062009
  • catalytic activity
    		•  1.03127962968326 bayes_pls_golite062009
  • monooxygenase activity
    		•  0.72374980280274 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.704326257168965 bayes_pls_golite062009
  • binding
    		•  0.694618787489897 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.556967966402473 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  0.442625746935807 bayes_pls_golite062009
  • protein binding
    		•  0.370064403093958 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.31459693204333 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  0.242456601435627 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.170082356807927 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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