Protein Overview: rdgB-PB, rdgB-PF

General Information:
Name(s) found:	rdgB-PF / FBpp0290748 [FlyBase] rdgB-PB / FBpp0073654 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7292924\|gb\|AAF48315.1\| retinal degeneration B, isoform B [Drosophila melanogaster] [NCBI NR] gi\|24641869\|ref\|NP_511149.2\| retinal degeneration B, isoform B [Drosophila melanogaster] [NCBI NR] The gene retinal degeneration B is referred to in FlyBase by the symbol Dmel\rdgB (CG11111, FBgn0003218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13656803..13670782. It has the cytological map location 12C1-12C4. There is experimental evidence that it has the molecular function</span>: phosphatidylcholine transmembrane transporter activity; phosphatidylinositol transporter activity. There is experimental evidence that it is involved in the biological process</span>: rhodopsin mediated signaling pathway; phototransduction; phosphoinositide metabolic process; deactivation of rhodopsin mediated signaling; sensory perception of smell. 48 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; compound cell cluster organ; adult segment; rhabdomere R7; mouthpart; rhabdomere; integumentary plate; cell projection; multi-cell-component structure. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase] >CG11111-PB translation from_gene[CG11111 rdgB FBgn0003218] seq_release:3 mol_weight=137842 cds_boundaries:(X:13,498,739..13,506,119[+]) aa_length:1250 transcript_info:[CG11111-RB seq_release:3] gene_info:[gene symbol:rdgB FBgn0003218 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] (Q9VY88) RDGB protein [DrosMelano7227.FASTAC.txt] (AE003493) rdgB gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta] (AE003493) rdgB gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta] CG11111-PB, isoform B [Drosophila melanogaster]gi\|24641869\|ref\|NP_511149.2\| CG11111-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=X:join(13662113..13662190,13662692..13662836,13662902..13663093,13663177..13663587,13663844..13664175,13665161..13665236,13665310..13666518,13666591..13666728,13666819..13667786,13667839..13668011,13669466..13669496); ID=FBpp0073654; nam [fly-100309-contam.fasta] retinal degeneration B CG11111-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG11111-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:join(13662113..13662190,13662692..13662836,13662902..13663093,13663177..13663587,13663844..13664175,13665161..13665236,13665310..13666518,13666591..13666728,13666819..13667786,13667839..13668011,13669466..13669496); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:join(13662113..13662190,13662692..13662836,13662902..13663093,13663177..13663587,13663844..13664175,13665161..13665236,13665310..13666518,13666591..13666728,13666819..13667786,13667839..13668011,13669466..13669496); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=X:join(13662113..13662190,13662692..13662836,13662902..13663093,13663177..13663587,13663844..13664175,13665161..13665236,13665310..13666518,13666591..13666728,13666819..13667786,13667839..13668011,13669466..13669496); ID=FBpp0290748; name=rdgB-PF; parent=FBgn0003218,FBtr0301533; dbxref=FlyBase:FBpp0290748,FlyBase_Annotation_IDs:CG11111-PF; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Isoform B of Protein retinal degeneration B OS=Drosophila melanogaster GN=rdgB [UniProt_drosophila_07-01-2011_reversed.fasta] Retinal degeneration B, isoform F OS=Drosophila melanogaster GN=rdgB PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:join(13662113..13662190,13662692..13662836,13662902..13663093,13663177..13663587,13663844..13664175,13665161..13665236,13665310..13666518,13666591..13666728,13666819..13667786,13667839..13668011,13669466..13669496); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315,FlyMine:FBpp0073654,modMine:FBpp0073654; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=X:join(13662113..13662190,13662692..13662836,13662902..13663093,13663177..13663587,13663844..13664175,13665161..13665236,13665310..13666518,13666591..13666728,13666819..13667786,13667839..13668011,13669466..13669496); ID=FBpp0290748; name=rdgB-PF; parent=FBgn0003218,FBtr0301533; dbxref=REFSEQ:NP_001162749,GB_protein:ACZ95284,FlyBase:FBpp0290748,FlyBase_Annotation_IDs:CG11111-PF; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315,FlyMine:FBpp0073654,modMine:FBpp0073654; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0290748; name=rdgB-PF; parent=FBgn0003218,FBtr0301533; dbxref=REFSEQ:NP_001162749,GB_protein:ACZ95284,FlyBase:FBpp0290748,FlyBase_Annotation_IDs:CG11111-PF; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315,FlyMine:FBpp0073654,modMine:FBpp0073654; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0290748; name=rdgB-PF; parent=FBgn0003218,FBtr0301533; dbxref=REFSEQ:NP_001162749,GB_protein:ACZ95284,FlyBase:FBpp0290748,FlyBase_Annotation_IDs:CG11111-PF; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of P43125, Retinal degeneration B, isoform F OS=Drosophila melanogaster GN=rdgB PE=1 SV=1 [DROME.fasta.20160308] Isoform of P43125, Isoform B of Protein retinal degeneration B OS=Drosophila melanogaster GN=rdgB [DROME.fasta.20160308] FBpp0073654 type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315,FlyMine:FBpp0073654,modMine:FBpp0073654; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0290748 type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0290748; name=rdgB-PF; parent=FBgn0003218,FBtr0301533; dbxref=REFSEQ:NP_001162749,GB_protein:ACZ95284,FlyBase:FBpp0290748,FlyBase_Annotation_IDs:CG11111-PF; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0073654; name=rdgB-PB; parent=FBgn0003218,FBtr0073823; dbxref=FlyBase:FBpp0073654,FlyBase_Annotation_IDs:CG11111-PB,GB_protein:AAF48315.1,REFSEQ:NP_511149,GB_protein:AAF48315,UniProt/TrEMBL:E1JJK7,FlyMine:FBpp0073654,modMine:FBpp0073654; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=X:join(13768080..13768157,13768659..13768803,13768869..13769060,13769144..13769554,13769811..13770142,13771128..13771203,13771277..13772485,13772558..13772695,13772786..13773753,13773806..13773978,13775433..13775463); ID=FBpp0290748; name=rdgB-PF; parent=FBgn0003218,FBtr0301533; dbxref=REFSEQ:NP_001162749,GB_protein:ACZ95284,FlyBase:FBpp0290748,FlyBase_Annotation_IDs:CG11111-PF,UniProt/TrEMBL:E1JJK7; MD5=837599b3cd813066e828e8f5dbd94951; length=1250; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1250 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIKEYRIPL PLTVEEYRIA QLYMIAKKSR EESHGEGSGV EIIINEPYKD GPGGNGQYTK  60
   61 KIYHVGNHLP GWIKSLLPKS ALTVEEEAWN AYPYTRTRYT CPFVEKFSLD IETYYYPDNG 120
  121 YQDNVFQLSG SDLRNRIVDV IDIVKDQLWG GDYVKEEDPK HFVSDKTGRG PLAEDWLEEY 180
  181 WREVKGKKQP TPRNMSLMTA YKICRVEFRY WGMQTKLEKF IHDVALRKMM LRAHRQAWAW 240
  241 QDEWFGLTIE DIRELERQTQ LALAKKMGGG EECSDDSVSE PYVSTAATAA STTGSERKKS 300
  301 APAVPPIVTQ QPPSAEASSD EEGEEEEDDD EDENDAIGTG VDLSANQGGS AQRSRSQSIQ 360
  361 MAQKGKFGSK GALHSPVGSA HSFDLQVANW RMERLEVDSK SNSDEEFFDC LDTNETNSLA 420
  421 KWSSLELLGE GDDSPPPHGG PSSAASVGGR GNSRQEDSIF NQDFLMRVAS ERGNKRQLRS 480
  481 SASVDRSHDS SPPGSPSTPS CPTTILILVV HAGSVLDAAS ELTAKKSDVT TFRGSFEAVM 540
  541 RQHYPSLLTH VTIKMVPCPS ICTDALGILS SLSPYSFDAS PSAADIPNIA DVPIGAIPLL 600
  601 SVASPEFHET VNKTVAAANI VYHEFLKSEE GHGFSGQIVM LGDSMGSLLA YEALCRSNGS 660
  661 QPGTASGASN SGGDAATNIN THNPLSPRNS RLDDDERFIE ADLDAKRLLV APSPRRRRSS 720
  721 SSSDSRATKL DFEVCDFFMF GSPLSVVLAA RKLHDAKAAL PRPNCHQVYN LFHPTDPIAS 780
  781 RLEPLLSARF SILAPVNVPR YAKYPLGNGQ PLHLLEVIQS HPQHFNDGNN LLAGRRLSDA 840
  841 SMQSTISGLI ENVSLSTIHA LQNKWWGTKR LDYALYCPEG LSNFPAHALP HLFHASYWES 900
  901 PDVIAFILRQ IGKFEGIPFV GSNDDKDNAS FHPGQPREKW IKKRTSVKLK NVAANHRAND 960
  961 VIVQEGREQR LNARFMYGPL DMITLHGEKV DVHIMKDPPA GEWTFLSTEV TDKNGRISYS1020
 1021 IPDQVSLGYG IYPVKMVVRG DHTSVDCYMA VVPPLTECVV FSIDGSFTAS MSVTGRDPKV1080
 1081 RAGAVDVCRH WQELGYLLIY ITGRPDMQQQ RVVSWLSQHN FPHGLISFAD GLSTDPLGHK1140
 1141 TAYLNNLVQN HGISITAAYG SSKDISVYTN VGMRTDQIFI VGKVGKKLQS NATVLSDGYA1200
 1201 AHLAGLQAVG GSRPAKGNAR MVIPRGCFNL PGQTANPRRR RLHEQATNEN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..282]	PSI-BLAST	123.0	Phoshatidylinositol transfer protein, PITP
2	View Details	[283..489]	MSA	2.084993	View MSA. No confident structure predictions are available.
3	View Details	[490..729]	MSA	2.110979	View MSA. No confident structure predictions are available.
4	View Details	[730..931]	Pfam	92.49485	No description for PF02862.8 was found. No confident structure predictions are available.
5	View Details	[932..1250]	FFAS03	2.58	No description for 2i33A was found.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: rdgB-PB, rdgB-PF

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: