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Protein Overview: sbr-PA

General Information:
Name(s) found: sbr-PA / FBpp0073267 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene small bristles is referred to in FlyBase by the symbol Dmel\sbr (CG1664, FBgn0003321). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10726785..10741125. It has the cytological map location 9F4-9F5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleotide binding. There is experimental evidence that it is involved in the biological process</span>: nuclear export; mRNA polyadenylation; poly(A)+ mRNA export from nucleus. 33 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; multi-cell-component structure; abdominal longitudinal muscle; intracellular membrane-bounded organelle; abdominal ventral longitudinal muscle 3; embryonic somatic muscle; ventral longitudinal muscle; embryonic nervous system; cell projection part; muscle attachment site. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 672 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    nuclear membrane [IDA]
    nucleoplasm [IDA][NAS]
    Biological Process: mRNA export from nucleus [IMP][NAS][TAS]
    long-term memory [NAS]
    nuclear export [IMP]
    adult behavior [NAS]
    poly(A)+ mRNA export from nucleus [IMP]
    mRNA polyadenylation [IMP]
    Molecular Function: nucleotide binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRGGGSSQ RYNNNVGNGG GRYNAPEDFD DFDVEDRQRR KDRNKRRVSF KPSQCLHNKK  60
   61 DIKLRPEDLR RWDEDDDMSD MTTAVKDRPT SRRRGSPIPR GKFGKLMPNS FGWYQVTLQN 120
  121 AQIYEKETLL SALLAAMSPH VFIPQYWRVE RNCVIFFTDD YEAAERIQHL GKNGHLPDGY 180
  181 RLMPRVRSGI PLVAIDDAFK EKMKVTMAKR YNIQTKALDL SRFHADPDLK QVFCPLFRQN 240
  241 VMGAAIDIMC DNIPDLEALN LNDNSISSME AFKGVEKRLP NLKILYLGDN KIPSLAHLVV 300
  301 LRNLSILELV LKNNPCRSRY KDSQQFISEV RRKFPKLVKL DGETLEPQIT FDLSEQGRLL 360
  361 ETKASYLCDV AGAEVVRQFL DQYFRIFDSG NRQALLDAYH EKAMLSISMP SASQAGRLNS 420
  421 FWKFNRNLRR LLNGEENRTR NLKYGRLACV STLDEWPKTQ HDRRTFTVDL TIYNTSMMVF 480
  481 TVTGLFKELN DETNNPASME LYDVRHFART YVVVPQNNGF CIRNETIFIT NATHEQVREF 540
  541 KRSQHQPAPG AMPSTSSAVT SPQAGAAAGL QGRLNALGVA TGPVAILSGD PLAATAPVNS 600
  601 GSAAISTTAV APGAQDESTK MQMIEAMSAQ SQMNVIWSRK CLEETNWDFN HAAFVFEKLF 660
  661 KENKIPPEAF MK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] deduced N/A No confident structure predictions are available.
    2 View Details [87..159] PSI-BLAST 38.221849 mRNA export factor tap
    3 View Details [160..497] PSI-BLAST 24.045757 No description for 2id5A was found.
    4 View Details [498..588] PSI-BLAST 29.221849 NTF2-like domain of Tip associating protein, TAP
    5 View Details [589..672] PSI-BLAST 15.69897 FG-binding, C-terminal domain of TAP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.40395910522193 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.96100267092334 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.81460663777944 bayes_pls_golite062009
  • DNA binding
    		•  1.67666753391185 bayes_pls_golite062009
  • small conjugating protein binding
    		•  1.17371403847093 bayes_pls_golite062009
  • protein binding
    		•  1.07513578953037 bayes_pls_golite062009
  • ubiquitin binding
    		•  0.83381750627184 bayes_pls_golite062009
  • catalytic activity
    		•  0.25774924710417 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle