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View Structure Prediction Details

Protein: sbr-PA
Organism: Drosophila melanogaster
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sbr-PA.

Description E-value Query
Range
Subject
Range
gi|109131615 - gi|109131615|ref|XP_001094356.1| PREDICTED: similar to nuclear RNA export factor 2 [Macaca mulatta]
366.0 [0..2] [672..161]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRGGGSSQ RYNNNVGNGG GRYNAPEDFD DFDVEDRQRR KDRNKRRVSF KPSQCLHNKK  60
   61 DIKLRPEDLR RWDEDDDMSD MTTAVK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRPTSRRRGS PIPRGKFGKL MPNSFGWYQV TLQNAQIYEK ETLLSALLAA MSPHVFIPQY  60
   61 WRVERNCVIF FTD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 1kooA
Description: mRNA export factor tap
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [160-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYEAAERIQH LGKNGHLPDG YRLMPRVRSG IPLVAIDDAF KEKMKVTMAK RYNIQTKALD  60
   61 LSRFHADPDL KQVFCPLFRQ NVMGAAIDIM CDNIPDLEAL NLNDNSISSM EAFKGVEKRL 120
  121 PNLKILYLGD NKIPSLAHLV VLRNLSILEL VLKNNPCRSR YKDSQQFISE VRRKFPKLVK 180
  181 LDGETLEPQI TFDLSEQGRL LETKASYLCD VAGAEVVRQF LDQYFRIFDS GNRQALLDAY 240
  241 HEKAMLSISM PSASQAGRLN SFWKFNRNLR RLLNGEENRT RNLKYGRLAC VSTLDEWPKT 300
  301 QHDRRTFTVD LTIYNTSMMV FTVTGLFKEL NDETNNPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.045757
Match: 2id5A
Description: No description for 2id5A was found.

Predicted Domain #4
Region A:
Residues: [498-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMELYDVRHF ARTYVVVPQN NGFCIRNETI FITNATHEQV REFKRSQHQP APGAMPSTSS  60
   61 AVTSPQAGAA AGLQGRLNAL GVATGPVAIL S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.221849
Match: 1jkgB
Description: NTF2-like domain of Tip associating protein, TAP
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [589-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDPLAATAPV NSGSAAISTT AVAPGAQDES TKMQMIEAMS AQSQMNVIWS RKCLEETNWD  60
   61 FNHAAFVFEK LFKENKIPPE AFMK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1go5A
Description: FG-binding, C-terminal domain of TAP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.40395910522193 bayes_pls_golite062009
transcription regulator activity 1.96100267092334 bayes_pls_golite062009
nucleic acid binding 1.81460663777944 bayes_pls_golite062009
DNA binding 1.67666753391185 bayes_pls_golite062009
small conjugating protein binding 1.17371403847093 bayes_pls_golite062009
protein binding 1.07513578953037 bayes_pls_golite062009
ubiquitin binding 0.83381750627184 bayes_pls_golite062009
catalytic activity 0.25774924710417 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle